This document provides instructions for preparing a 240mL suspension of sevelamer with a concentration of 50mg/mL. It lists the necessary equipment, ingredients, and references. The directions involve placing sevelamer tablets in a beaker, adding water to allow disintegration, mixing in simple syrup as the vehicle, and transferring to a graduate for final volume adjustment. Quality control was performed on 4/7/2010 and storage is noted as refrigeration for up to 14 days.
This document provides instructions for preparing a 240mL suspension of sevelamer with a concentration of 50mg/mL. It lists the necessary equipment, ingredients, and references. The directions involve placing sevelamer tablets in a beaker, adding water to allow disintegration, mixing in simple syrup as the vehicle, and transferring to a graduate for final volume adjustment. Quality control was performed on 4/7/2010 and storage is noted as refrigeration for up to 14 days.
This document provides instructions for preparing a 240mL suspension of sevelamer with a concentration of 50mg/mL. It lists the necessary equipment, ingredients, and references. The directions involve placing sevelamer tablets in a beaker, adding water to allow disintegration, mixing in simple syrup as the vehicle, and transferring to a graduate for final volume adjustment. Quality control was performed on 4/7/2010 and storage is noted as refrigeration for up to 14 days.
Drug Name Route Dosage Form Concentration Sevelamer Oral Suspension 50mg/mL
Formula Qty: 240mL Shelf Life: 14 days
Equipment needed: Glass beaker, graduated cylinder, stirring rod
Auxiliary Labels/Storage: Shake Well; Refrigerate No room temperature stability information. Directions: 1. Place tablets in a beaker. 2. Add distilled water and allow tablets to disintegrate. Stir occasionally. 3. Add a portion of vehicle and mix to form a uniform suspension. 4. Transfer to a graduate. 5. QS to final volume with vehicle. Stir well.
Ingredients QS Quantity Units Sevelamer 800mg Tablets 15 Tablets Distilled Water 120 mL Simple Syrup, NF X 240 mL
Citations/References McElhiney, LF. Sevelamer Suspension in Children with End-Stage Renal Disease. IJPC. 2007. 11(1): 20-24. Reviewed: 4/7/2010 JEB
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