DRUG STUDY

Indication/ Contraindication

Mechanism of Action
Side Effects/ Adverse Effect Nursing Considerations


Generic Name:
Budesonide

Classification:
Corticisteroids

Dosage:
250 mcg/mL 2mL

Therapeutic Dose:
respule + 2mL NSS

Frequency:
Every 12 hours

Route:
Inhalation

Date ordered:
August 31, 2013

Indications:Treatment &
prevention of nasal polyps after
polypectomy. Management
ofbronchial asthma
andsymptomatic managementof
seasonal or perennialallergic
rhinitis.
Contraindications:Not intended
for rapid relief of acute episodes
of asthma where an inhaled
short-acting bronchodilator is
required. Primary treatment of
acuteasthmatic attacks or
statusasthmaticus whenintensive
measures arerequired.
Hypersensitivityto budesonide.



Exerts a local anti-inflammatory
effect by depression of migration
of polymorphonuclear
leukocytes and lyesosomal
stabilization. It does not
permeability and lysosomal
stabilization. It does not
suppress hypothalamus and
pituitary function. Anti-
inflammatoryeffect;
localadministrationinto
nasalpassagesmaximizesbenefici
al effectson these tissues,while
decreasingthe likelihood
of adverse effectsfrom
systemicabsorption.


Therapeutic Effect: Reduces
swelling of the respiratory tract
allowing easier breathing.
Maintenance treatment and
prophylaxis therapy of asthma in
children 12mo-8yo
Side Effects: Headaches,
Sensitive skin, Nausea or
vomiting, Dry cough or sore
throat, Muscle or joint pain,
Disturbance in menstrual cycles
Adverse Effects: Chest pain,
Ulceration of the nasal septum,
Candidiasis of the mouth,
Fungal infection, Stinging,
Sneezing, Pharyngitis, Urticaria,
Alopecia, Angioedema,
Bronchospasm, Face and tongue
edema, Pruritus, Wheezing,
Dyspnea
Assess respiratory status: rate,
rhythm, increased in bronchial
secretions, wheezing, and chest
tightness.
Provide at least 2L/day of fluids
to decrease viscosity of
secretions.
Check for oral candidiasis
Carefully assess presence of viral
infections, corticosteroid use can
mask infections
If bronchospasm occurs, stop
treatment and give bronchodilator
Arrange for use of decongestant
nose drops to facilitate
penetration if edema, excessive
secretions are present.
Store respule upright and
protected from light, gently shake
before use.
Prime unit before use for
PulmicortTurbuhaler
Have patient rinse mouth after
each use.