A double-blind randomized controlled trial compared the efficacy and safety of 3-day and 7-day courses of oral ciprofloxacin for uncomplicated urinary tract infections in older women. 243 women aged 65 or older with acute uncomplicated UTIs were randomly assigned to receive ciprofloxacin 500 mg twice daily for either 3 days followed by placebo for 4 days, or ciprofloxacin 500 mg twice daily for 7 days. The primary outcomes measured were antimicrobial efficacy at 14 days after treatment and risk of relapse or reinfection at 6 weeks after treatment completion.
A double-blind randomized controlled trial compared the efficacy and safety of 3-day and 7-day courses of oral ciprofloxacin for uncomplicated urinary tract infections in older women. 243 women aged 65 or older with acute uncomplicated UTIs were randomly assigned to receive ciprofloxacin 500 mg twice daily for either 3 days followed by placebo for 4 days, or ciprofloxacin 500 mg twice daily for 7 days. The primary outcomes measured were antimicrobial efficacy at 14 days after treatment and risk of relapse or reinfection at 6 weeks after treatment completion.
A double-blind randomized controlled trial compared the efficacy and safety of 3-day and 7-day courses of oral ciprofloxacin for uncomplicated urinary tract infections in older women. 243 women aged 65 or older with acute uncomplicated UTIs were randomly assigned to receive ciprofloxacin 500 mg twice daily for either 3 days followed by placebo for 4 days, or ciprofloxacin 500 mg twice daily for 7 days. The primary outcomes measured were antimicrobial efficacy at 14 days after treatment and risk of relapse or reinfection at 6 weeks after treatment completion.
A double-blind randomized controlled trial compared the efficacy and safety of 3-day and 7-day courses of oral ciprofloxacin for uncomplicated urinary tract infections in older women. 243 women aged 65 or older with acute uncomplicated UTIs were randomly assigned to receive ciprofloxacin 500 mg twice daily for either 3 days followed by placebo for 4 days, or ciprofloxacin 500 mg twice daily for 7 days. The primary outcomes measured were antimicrobial efficacy at 14 days after treatment and risk of relapse or reinfection at 6 weeks after treatment completion.
Optimal duration of antibiotic therapy for uncomplicated
urinary tract infection in older women: a double-blind
randomized controlled trial Thomas Vogel, et al Background The optimal duration of antibiotic therapy in older patients with uncomplicated urinary tract infection (UTI) is still a matter of debate A short course of treatment might offer significant advantages in terms in proved compliance and fewer drug interaction and side effect Objectie To compare the efficacy and safety of 3 day and 7 day courses of oral ciprofloxacin for uncomplicated symptomatic UTI in older women !ethod A double!blind randomi"ed controlled trial A total of #$3 women at least %& years of age with acute uncomplicated symptomatic UTI were recruitment 'omen were randomly assigned to received either ciprofloxacin (&) mg twice daily orally for 3 day follow by placebo * day (+3 patients), and randomly assigned to received ciprofloxacin (&) mg twice daily orally for 7 day ( +) patients) -rimary outcome were antimicrobial efficacy at ( days after completion of treatment and ris. of relaps and reinfection at % wee.s after completion of treatment # (