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Millionaireproject
Millionaireproject
ByJackMuffin,JasonFranks,PeterHunt,KyleJones,RonanShaffer
Unmetneed:Thenaturalcureforcancerthroughproteinsincancerouscells.
ProjectIdea:TouseTIC10asanaturaltumorresistor.
Materialsneeded:
lab(needsqfeet)
tumors
mice
50mgofTIC10$350
100microgramsofactivehumanTRAILprotein$198
scientists
employees
TRAILstandsforTumornecrosisfactorrelatedapoptosisinducingligandorApo2ligand.
BackgroundonTRAIL
TRAILisamemberofatumorkillingmoleculefamilythatsjobistoinitiateapoptoticsuicide.
TRAILisauniquemoleculebecauseitkillsonlytransformedcells,notnormalcells.TRAILis
notcompletelyeffectivebecausesometumorshavedevelopedTRAILresistance.Apoptosis
producescellfragmentscalledapoptosisbodiesthatphagocyticcellsengulfandquicklyremove
thecontentsofthecell.
Problem
WhydosometumorstodevelopTRAILresistance?
Solution
Asamateursinthisareaofscience,Ibelievethatwewouldnotbeabletofigureoutwhysome
tumorsdevelopresistancetotheTRAILprotein.Whatwecandoiscreatealaboratorywhere
wegivethebestscientiststheopportunitytosolvethisproblem.IDEACombinearesistance
proteinwiththeTRAILprotein.
FacilitiesneededtomakeMaterials.
lab(needsqfeet)
Estimatedcostofdevelopment
Howmanyunitsshouldbemadeforthemarket
Asmanyaspossible.
Timeline(productionandtimetodevelopproduct)
Market(whowillbebuyingthis)
Anybodywhohascancerwillbebuyingourproduct.
Bibliography
http://www.nature.com/onc/journal/v22/n53/full/1207232a.html