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46 PDF
Stock/Shareholder: N/A
Consultant: Sanofi; Lilly
Employee: N/A
Other: N/A
Study sponsored by Sanofi
Background
Many youths with T1D are still not meeting HbA1c targets1,2
Diabetes management is a burden, with many barriers to
achieving target glycemic control, especially for adolescents.3
Further understanding of these challenges could improve
diabetes outcomes
TEENs study
is the largest worldwide, contemporary, observational study
and has assessed the main factors associated with HbA1c target
attainment in 5,960 youth with T1D, aged 825 years old (y/o)
Aim:
This analysis of TEENs describes associations between
diabetes education needs, management of food intake and
attainment of HbA1c target
1. Wood JR, et al. Diabetes Care 2013; 36 (7): 20357; 2. Laffel LM, et al. Diabetes 2014; 63 (Suppl. 1); Abstract 32-OR;
3. Borus JS, et al. Curr Opin Pediatr 2010; 22 (4): 40511.
USA
25 sites
499 participants
LATIN AMERICA
(Argentina/Mexico)
27 sites
470 participants
EUROPE
(Denmark/France/Germany/Hungary/Italy/
Portugal/Romania/Russia/Slovenia/
Spain/Sweden)
111 sites
2943 participants
SOUTH AFRICA
5 sites
507 participants
MIDDLE EAST/NORTH
AFRICA
Algeria/Jordan/
Lebanon/Morocco
33 sites
1041 participants
INDIA
18 sites
500 participants
Methods
Mean (SD) duration of T1D was 4.5 (2.7) years in 812 y/o,
6.6 (3.8) years in 1318 y/o, and 11 (4.9) years in 1925 y/o
72% of study participants did not attain HbA1c target*
HbA1c target met
Participants, %
100
80
60
40
20
32
29
812
(n=1723)
1318
(n=2854)
19
1925
(n=1382)
HbA1c target
12
10
8
6
4
8,3
8,6
8,4
812
1318
1925
2
0
(n=1723)
(n=2854)
(n=1381)
Age group, y/o
HbA1c
target* met
HbA1c target
not met
34
40
34
24
25
27
37
39
37
26
28
30
812 y/o
1318 y/o
1925 y/o
45
Proportion of
participants (%)
40
35
30
41
41
35
35
40
36
25
20
15
10
5
0
Managing T1D during illness
812 y/o
1318 y/o
1925 y/o
45
Proportion of
participants (%)
40
35
30
36
37
33
30
25
27
23
20
15
10
5
0
Nutrition and dietary issues
Carbohydrate counting
812 y/o
1318 y/o
1925 y/o
45
Proportion of
participants (%)
40
35
30
25
20
34
31
29
27
23
26
15
10
5
0
Insulin administration
0,5
1,5
2,5
Based on experience
Weighing/measuring
Avoiding sugars
100
90
80
6
6
7
11
5
8
70
60
34
35
50
Carbohydrate exchanges
40
30
20
45
38
10
0
HbA1c
target
HbA
1c target met
met
target
HbAHbA1c
1c target not met
not met
*HbA1c targets:
Conclusions
Desire for more education was seen across all age groups
Associated with HbA1c target attainment: if interested (vs
not) in learning more about
high-risk behaviors
continuous glucose monitoring
Acknowledgements