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Drugs

Classification

Generic:
Ranitidine

Gastointestinal
agents:

Brand:
Zantac

Antisecretory
(H2- receptor
antagonist)

Indication

Dose/
Route And
Frequency

Used to
50mg Q8
prevent
IVTT while
ulcer while
NPO
patient is on
NPO

Mechanism Of
Action

Contraindication

Competitiveinhi
bition
of histamine at
H2-receptors of
thegastric
parietalcells,
which
inhibitsgastric
acidsecretion,
gastricvolume,
andhydrogen
ionconcentration
arereduced.
Does notaffect
pepsinsecretion,
pentagastrinstimulated
intrinsicfactor
secretion,
or serum
gastrin.

Hypersensitivity
toranitidine or
anycomponent of
theformulation.

Side Effect

Constipatio
n
Diarrhea
Fatigue
Headache
Insomnia
Muscle pain
Nausea
Vomiting
Agitation
Anemia
Confusion
Depression
Easy
bruisingor
bleeding

Nursing
Responsibilities

Assess patient for


epigastric or
abdominal pain
and frank or occult
blood in the stool,
emesis, or
gastric aspirate.
Inform patient that
it may cause
drowsiness or
dizziness.
Inform patient that
increased fluid and
fiber intake may
minimize
constipation.
Inform patient that
medication may
temporarily cause
stools and tongue
to appear gray b
lack

Drugs

Classification Indication

Antiprotozoal
Diloxanide
furoate

The drug is
used in
intestinal
amoebiasis
and is given
after any
tissue
amoebicide
to eradicate
cysts

Dose/
Route And
Frequency

PO 500mg
3x a day for
ten days

Mechanism Of
Action

Contraindication

Side Effect

Luminal
amebicide.
{
The
mechanism of
action of
diloxanide is
unknown. This
agent destroys
the
trophozoites of
E. histolytica
that eventually
form into cysts.
The cysts are
then excreted
by persons
infected with
asymptomatic
amebiasis.

Hypersensitivity

Flatulence,
loss of
appetite,
nausea,
vomiting,
itching and
hives

Nursing
Responsibilities

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