Name: RAFAEL, DUNE VIENIS KAREN N.

Year & Section: BS-

Pharmacy 4A
Group Number: ___________________ Date Started: November
27, 2009
Date Submitted: December 7,
2009

Exercise No. 9
ADRENALINE AMPOULE FOR INTRAVENOUS USE

I. Objectives:
i. To attain skills in preparing adrenaline intravenous injection
ii. To know the precautions in preparing adrenaline intravenous
injection, and
iii. To analyze the mechanism of action of intravenous adrenalin.

I. Data Output:
Saint Luke’s Hospital
Father Selga Street, Davao City
Patient’s Name: Robert John R. Rafael Age: 23 Sex: Male
Attending Physician: J. Noveno, MD. Room No.: 47

Epinephrine
1 mg/ml solution for intravenous use

Prepared by: Dune Rafael, RPh

Pharmacist

II. Answers to Questions:

1. Describe the mechanism of action of Adrenalin as intravenous
injection.
Adrenalin (epinephrine) is a sympathomimetic drug. It activates
an adrenergic receptive mechanism on effector cells and imitates all
actions of the sympathetic nervous system except those on the
arteries of the face and sweat glands. Epinephrine acts on both alpha
and beta receptors and is the most potent alpha receptor activator
[Rxlist, 2009].

2. What particular circumstances is an intravenous injection of adrenaline

applied?
Intravenous injection of adrenaline is applied in cases of cardiac
emergencies to restore cardiac rhythm in cardiac arrest due to various
causes, but it is not used in cardiac failure or in hemorrhagic,
traumatic, or cardiogenic shock [Rxlist, 2009].

I. Conclusions:

Adrenalin (epinephrine) is a sympathomimetic drug. It activates

an adrenergic receptive mechanism on effector cells and imitates all
actions of the sympathetic nervous system except those on the
arteries of the face and sweat glands. Epinephrine acts on both alpha
 and beta receptors and is the most potent alpha receptor activator.
Intravenous injection of adrenaline is applied in cases of cardiac
emergencies to restore cardiac rhythm in cardiac arrest due to various
causes, but it is not used in cardiac failure or in hemorrhagic,
traumatic, or cardiogenic shock.

Adrenaline is sensitive to light exposure. Therefore, adrenalin

preparations must be kept away from light as much as possible. It
should also be inspected visually for particulate matter or
discoloration.

II. Bibliography:

Rxlist. (2009, March 03). Adrenalin (Epinephrine) Drug Information. Retrieved

December 07, 2009, from Rxlist.com: http://www.rxlist.com/adrenalin-drug.htm