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Bioreactors: An Artificial Life Support System: Presented By: Mitesh Shrestha
Bioreactors: An Artificial Life Support System: Presented By: Mitesh Shrestha
Bioreactors: An Artificial Life Support System: Presented By: Mitesh Shrestha
Presented by:
MITESH SHRESTHA
Contents
Introduction to Bioreactors
Types of Bioreactor designs
Conclusion
Bioreactors
Advantages
Disadvantages
Can cause damage to the cells
High energy demand
Complexity in construction
Difficult to scale up.
Bubble-column reactors
Advantages
Disadvantages
Air-lift reactors
Advantages
Less contamination
Disadvantages
Advantages
High oxygen transfer.
Good mixing
Facilitated better growth and impart less
hydrodynamic stress.
Disadvantages
Membrane reactors
Advantages
Hydrodynamic Mixing
stress
Stirred-tank
Highly
destructive
Completely Difficult
uniform
Cell death;
contamination due
to moving parts
ST-low
Medium
agitation and
modified
impeller
Low
Reasonably Difficult
uniform
Insufficient mixing
at very high cell
densities
Bubblecolumn
Medium
Low
Nonuniform
Easy
Dead zones;
settling of cells due
to poor mixing
Air-lift
High
Low
Uniform
Easy
Rotatingdrum
High
Low
Uniform
Difficult
Non-uniform
mixing at very
large scale.
High
Scale up
limitations
Conclusion
Thank you !