BAB IV Disolusi

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BAB IV

HASIL PENGAMATAN

VI.1 Data Pengamatan


No.
1.
2.
3.
4.

Waktu
5
10
30
45

V1
0,4
0,4
0,6
0,4

V2
0,6
0,3
0,2
0,2

VI.2. Perhitungan
A. Perhitungan Kadar
%K

N x V x Bst
Bs

t = 5

% K1 =

% K2 =
% Krata2 =

x 100 %

0,0979 x 0,4 x 52,43


100
0,0979 x 0,6 x 52,43
100
2,053 + 3,079
2

x 100 %

= 2,053 %

x 100 %

= 3,079 %

= 2,566 %

t = 10

% K1 =

% K2 =
% Krata2 =

t = 30

% K1 =

% K2 =
% Krata2 =

t = 45

% K1 =

% K2 =
% Krata2 =

0,0979 x 0,4 x 52,43


100
0,0979 x 0,3 x 52,43
100
2,053 + 1,539
2

0,0979 x 0,6 x 52,43


100
0,0979 x 0,2 x 52,43
100
3,079 + 1,026
2

0,0979 x 0,4 x 52,43


100
0,0979 x 0,2 x 52,43
100
2,053 + 1,026
2

x 100 %

= 2,053 %

x 100 %

= 1,539 %

= 1,796 %

x 100 %

= 3,079 %

x 100 %

= 1,026 %

= 2,052 %

x 100 %

= 2,053 %

x 100 %

= 1,026 %

= 1,539 %

B. Bobot zat aktif


Wa

% K x 900 ml

= 2309,4 mg

t = 5

Wa

= 2,566 % x 900 ml = 2309,4 mg

t = 10

Wa

= 1,796 % x 900 ml = 1616,4 mg

t = 30

Wa

= 2,052 % x 900 ml = 1846,8 mg

t = 45

Wa

= 1,539 % x 900 ml = 1385,1 mg

C. Persen kelarutan
%K

t = 5

%K

t = 10

%K

t = 30

%K

t = 45

%K

500
2309,4

500
1616,4

500
1846,8

500
1385,1

Wn
Wa

x 100 %

x 100 %

= 21,65 %

x 100 %

= 30,93 %

x 100 %

= 27,07 %

x 100 %

= 36,09 %

D. Perhitungan regresi
Waktu
5

Log (Wa Wn)


3,25

10

3,04

30

3,12

45

2,94

Dari hasil regresi, maka nilai


a

= 3,204

= -0,0051

= a + bx

maka persamaan garis linear


y

= a + bx

= 3,204 - 0,0051 x

= 2,303 x b
= 2,303 x (- 0,0051)
= - 0,0117

t1/2 = 0,693 / K
= 0,693 / 0,0117
= 59,23 menit

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