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    Triple Reuptake

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    This document discusses several triple reuptake inhibitors (TRIs), which are drugs that inhibit the reuptake of serotonin, norepinephrine, and dopamine. It lists the chemical structures and names of several TRIs, including DOV 216,303, GSK-372,475, sibutramine, bupropion, and SEP-225289. These drugs work by increasing the levels of three key neurotransmitters in the brain.

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    Triple Reuptake

    Uploaded by

    dissention
    26K views1 page
    This document discusses several triple reuptake inhibitors (TRIs), which are drugs that inhibit the reuptake of serotonin, norepinephrine, and dopamine. It lists the chemical structures and names of several TRIs, including DOV 216,303, GSK-372,475, sibutramine, bupropion, and SEP-225289. These drugs work by increasing the levels of three key neurotransmitters in the brain.

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    This document discusses several triple reuptake inhibitors (TRIs), which are drugs that inhibit the reuptake of serotonin, norepinephrine, and dopamine. It lists the chemical structures and names of several TRIs, including DOV 216,303, GSK-372,475, sibutramine, bupropion, and SEP-225289. These drugs work by increasing the levels of three key neurotransmitters in the brain.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pdf or txt
    26K views1 page

    Triple Reuptake

    Uploaded by

    dissention
    This document discusses several triple reuptake inhibitors (TRIs), which are drugs that inhibit the reuptake of serotonin, norepinephrine, and dopamine. It lists the chemical structures and names of several TRIs, including DOV 216,303, GSK-372,475, sibutramine, bupropion, and SEP-225289. These drugs work by increasing the levels of three key neurotransmitters in the brain.

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    Triple Reuptake Inhibitors (TRIs)

    Cl

    H2N

    H2N Cl
    CH3

    N CH3
    Cl
    H3C

    2 CH3
    NH

    1
    Cl
    3 2
    Cl
    3 Sibutramine
    2 HN
    1 Cl

    DOV 216, 303 O

    CH3
    Cl

    O CH3
    Cl GSK-372,475 HN
    1
    CH3
    2 CH3
    Cl H3C
    H3C NH2
    Bupropion
    CH3
    SEP-225289

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