DRUG DESIGNING

BY,
V.SRI HARSHA
REG
NO:1091110136

DRUG DESIGNING : It is theinventiveprocess of finding

newmedicationsbased on the knowledge of a biological
target.Thedrugis most commonly anorganicsmall
moleculethat activates or inhibits the function of
abiomoleculesuch as aprotein, which in turn results in a
therapeuticbenefit to thepatient.In the most basic sense,
drug design involves the design of smallmoleculesthat
are complementary inshape andchargeto the
biomolecular target with which they interact and therefore
will bind to it.

LIGAND:Incoordination chemistry, aligand is

anionormolecule(functional group) that binds to a
centralmetalatom to form acoordination complex. The
bonding betweenmetaland ligand generally involves formal
donation of one ormoreof the ligand'selectron pairs. The
nature of metal-ligandbonding can range fromcovalentto
ionic. Furthermore, the metal-ligandbond ordercan range
from one to three. Ligands are viewed asLewis bases,
although rare cases are known to involveLewis acidic"ligand.
RECEPTOR: