71078

) '(

:
Protein Synthesis

 : , ,

mRNA ,
,

UTR
UTR

: mRNA - )
(
mRNA - '5 '3

.

 tRNA-

tRNA Structure

) 75-80( " tRNA "

" " . tRNA 61

rRNA and Ribosomes

rRNA )(Nucleolus
rRNA


,

 "
" ) " (S s60
) s50( s30) s40(

(Activation) .1
(Initiation) .2
(Elongation) .3
(Termination) .4

Protein Synthesis- Activation

Aminoacyl- tRNA

anticodon
codon

anticodon
Aminoacyl-tRNA
synthase

tRNA ) (ATP + "

tRNA tRNA
.1 : " ) ( .2 ) tRNA (
20 20
tRNA

Interaction Between the Three RNAs

 )(Initiation
) MET tRNA (UAC


'5 mRNA
'3

)(AUG

'3

=< "

The Ribosome Subunits

MET tRNA
,P tRNA A

)(Exit) (Peptidyl) (Aminoacyl

 )(Elongation
A
tRNA

"

eEF1
GTP tRNA

 '3 tRNA
P E .

 )(Termination

)(stop codon

Stages in Protein Synthesis

Protein Synthesis- Polyribosomes

 "

 mRNA

Polyribosome in Protein Synthesis

,
,
5 , 3

,
mRNA .

=<