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Environment Triggers - Hormones - Infections Drugs UV Radiation - Age - Genetics - Medications - Lifestyle - Diet
Environment Triggers - Hormones - Infections Drugs UV Radiation - Age - Genetics - Medications - Lifestyle - Diet
-Environment
triggers
-hormones
-Infections
Drugs
UV radiation
Vascular Injury
Abnormal Constriction of Blood vessels
Overgrowth of endothelial & muscle of blood vessels
Endothelial cells dysfunction and activation
Corticosteroids
Modifiable:
- Medications
- Lifestyle
-Diet
Vasoactive mediators
Vasculopathy
Tissue hypoxia
Platelet activation
Pepsin Release
Histamine
Fibroblast activation
Overproduction of Collagen & and fibronectin in the dermis
Fibrosis of skin & organs
Acid secretion
Mucosal erosion
Vasodilatation
Destruction of blood vessels
Muscle spasm
Epidermal Atrophy
capillary permeability
Epigastric pain
Acute Gastritis
NonModifiable:
- Age
-Genetics
-