Drug Name

Mechanism of
Action

Administration

Generic
Name:
Morphine
Sulfate

Principal
opium
alkaloid acts
as agonist at
specific
oploid
receptors in
the CNS to
produce
analgesia,
euphoria,
sedation

2.5-1.5
mg/70kg of
body weight.
4-5ml water
for injection
over 4-5min

Brand
Name:
Astramorph,
Daramorph,
Epimorph

Classification:
Oploid agonist
analgesic

Indication

Contraindicatio
n

Adverse
Effect

Nursing
Responsibilities

-Relief
moderate to
severe acute
and chronic
pain.
-Analgesics
adjust during
anesthesia.
-Intaspinal use
with
microfusion
devices for the
relief of
intractable
pain.

Contraindicate
d to patients
with
hypersensitivit
y to opoids.
Use cautiously
with acute
asthma, cor
pulmonale,
hypoxia,
hypercapnia

Flushing,
tachycardia,
bradycardia,
arrythmia,
palpitations,
hypertension

-Dilute administer
slowly IV to minimize
adverse effects.
-Avoid alcohol, antihistamines, sedatives,
tranquilizers during
medication.
-Report severe
nausea, vomiting,
shortness of breath.