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    Angiotensin-Neprilysin Inhibition Versus Enalapril

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    The document describes a clinical trial that compared the effects of angiotensin-neprilysin inhibition versus enalapril in patients with heart failure. The trial found that angiotensin-neprilysin inhibition reduced the risks of cardiovascular death and hospitalization for heart failure more than enalapril alone in patients with heart failure with reduced ejection fraction. Angiotensin-neprilysin inhibition provided greater reduction in risks than the current standard treatment of enalapril.

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    Angiotensin-Neprilysin Inhibition Versus Enalapril

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    Solaris_movement
    12 views2 pages
    The document describes a clinical trial that compared the effects of angiotensin-neprilysin inhibition versus enalapril in patients with heart failure. The trial found that angiotensin-neprilysin inhibition reduced the risks of cardiovascular death and hospitalization for heart failure more than enalapril alone in patients with heart failure with reduced ejection fraction. Angiotensin-neprilysin inhibition provided greater reduction in risks than the current standard treatment of enalapril.

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    Angiotensin–Neprilysin Inhibition Versus Enalapril

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    The document describes a clinical trial that compared the effects of angiotensin-neprilysin inhibition versus enalapril in patients with heart failure. The trial found that angiotensin-neprilysin inhibition reduced the risks of cardiovascular death and hospitalization for heart failure more than enalapril alone in patients with heart failure with reduced ejection fraction. Angiotensin-neprilysin inhibition provided greater reduction in risks than the current standard treatment of enalapril.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
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    12 views2 pages

    Angiotensin-Neprilysin Inhibition Versus Enalapril

    Uploaded by

    Solaris_movement
    The document describes a clinical trial that compared the effects of angiotensin-neprilysin inhibition versus enalapril in patients with heart failure. The trial found that angiotensin-neprilysin inhibition reduced the risks of cardiovascular death and hospitalization for heart failure more than enalapril alone in patients with heart failure with reduced ejection fraction. Angiotensin-neprilysin inhibition provided greater reduction in risks than the current standard treatment of enalapril.

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    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
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    of 2

    AngiotensinNeprilysin Inhibition

    versus Enalapril
    in Heart Failure
    John J.V. McMurray, M.D., Milton Packer, M.D., Akshay S. Desai,
    M.D., M.P.H., Jianjian Gong, Ph.D.,
    Martin P. Lefkowitz, M.D., Adel R. Rizkala, Pharm.D., Jean L.
    Rouleau, M.D., Victor C. Shi, M.D.,
    Scott D. Solomon, M.D., Karl Swedberg, M.D., Ph.D., and Michael R.
    Zile, M.D.,
    september 11, 2014 The new england journal of
    for the PARADIGM-HF Investigators
    and Committees*
    medicine

    Introducere
    Tratamentul cu IEC, un tratament de
    referinta in I.C., cu reducerea
    semnificativa a mortalitatii, cu pana
    la 16% la pacientii cu simptome
    usoare spre moderate.
    Efectul ARB asupra mortalitatii este
    incert.
    Tripla terapie in IC (beta-blocanti,
    antialdosteronice, IEC ) reduc
    mortalitate cu 30-35%

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