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    WBC Morphology

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    This document summarizes the five main types of leukocytes or white blood cells (WBCs): neutrophils, eosinophils, basophils, lymphocytes, and monocytes. It provides details on the morphology and physiology of each cell type. Neutrophils are the most abundant WBC and respond first to bacteria through phagocytosis and release of chemicals. Eosinophils combat parasites and act on antigen-antibody complexes. Basophils mature into mast cells and release inflammatory mediators. Lymphocytes circulate throughout the body. Monocytes differentiate into macrophages to remove microbes and cellular debris.

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    WBC Morphology

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    Glucose DRglucose
    83 views10 pages
    This document summarizes the five main types of leukocytes or white blood cells (WBCs): neutrophils, eosinophils, basophils, lymphocytes, and monocytes. It provides details on the morphology and physiology of each cell type. Neutrophils are the most abundant WBC and respond first to bacteria through phagocytosis and release of chemicals. Eosinophils combat parasites and act on antigen-antibody complexes. Basophils mature into mast cells and release inflammatory mediators. Lymphocytes circulate throughout the body. Monocytes differentiate into macrophages to remove microbes and cellular debris.

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    WBC Morphology

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    This document summarizes the five main types of leukocytes or white blood cells (WBCs): neutrophils, eosinophils, basophils, lymphocytes, and monocytes. It provides details on the morphology and physiology of each cell type. Neutrophils are the most abundant WBC and respond first to bacteria through phagocytosis and release of chemicals. Eosinophils combat parasites and act on antigen-antibody complexes. Basophils mature into mast cells and release inflammatory mediators. Lymphocytes circulate throughout the body. Monocytes differentiate into macrophages to remove microbes and cellular debris.

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    83 views10 pages

    WBC Morphology

    Uploaded by

    Glucose DRglucose
    This document summarizes the five main types of leukocytes or white blood cells (WBCs): neutrophils, eosinophils, basophils, lymphocytes, and monocytes. It provides details on the morphology and physiology of each cell type. Neutrophils are the most abundant WBC and respond first to bacteria through phagocytosis and release of chemicals. Eosinophils combat parasites and act on antigen-antibody complexes. Basophils mature into mast cells and release inflammatory mediators. Lymphocytes circulate throughout the body. Monocytes differentiate into macrophages to remove microbes and cellular debris.

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    of 10

    CH 17 WBC

    Morphology

    Five Types of Leukocytes (WBCs)

    Granular Leukocytes
    Eosinophil

    Neutrophil
    Basophil

    Neutrophil
    60-70% of all WBCs
    Anatomy

    10-12 m diameter
    2-6 nuclear lobes
    Fine, pale inconspicuous
    granules

    Physiology

    Respond first to bacteria


    damage by chemotaxis
    Phagocytosis
    After engulfing pathogen
    releases several chemicals

    lysozyme
    strong oxidants
    defensins

    Eosinophil

    2-4% of all WBCs


    Anatomy
    10-12 m diameter
    2 connected nuclear
    lobes
    red/orange large,
    uniform granules, do
    not obscure the
    nucleus
    Physiology
    exit capillaries, enter
    tissue fluid
    combat parasites

    histamine

    phagocytize antigenantibody complexes

    Basophil

    0.5-1% of all WBCs


    Anatomy

    8-10 m diameter
    bilobed or irregular
    nucleus
    round, blue-black
    granules may obscure
    the nucleus

    Physiology

    exit capillaries to enter


    tissue fluid
    mature into mast cells

    release heparin,
    histamine, serotonin
    stimulate inflammation

    Hypersensitivity
    (allergic) reactions

    Agranular Leukocytes

    Lymphocyte
    Monocyt
    e

    Lymphocytes
    20-25% of all
    WBCs
    Anatomy

    7-15m
    nucleus large and
    dark stained,
    round or indented
    cytoplasm forms
    a pale blue rim
    around the
    nucleus

    Monocytes
    3-8% of all WBCs
    Anatomy

    14-19 m
    indented or kidney-shaped
    nucleus (not round)
    cytoplasm foamy

    Physiology

    slower to arrive but


    survive longer
    enlarge, differentiate into
    fixed and wandering
    macrophages
    remove microbes, cellular
    debris, following injury

    End
    WBC Morphology

    CH 17

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