Scribd Logo
Upload

Welcome to Scribd!

  • Fusion Inhibitors

    Uploaded by

    Falaq2
    19 views1 page
    Enfuvirtide is a fusion inhibitor that interferes with HIV-1 entry into CD4 cells by inhibiting the fusion of viral and cellular membranes. It is a 36-amino-acid synthetic peptide administered through subcutaneous injections twice daily into the arm, thigh, or abdomen. Common adverse effects include hypersensitivity reactions and injection site discomfort, but it has an improved safety profile compared to other antiretrovirals since it does not act inside host cells and is metabolized to amino acids with no interactions with other medications.

    Original Description:

    Fusion Inhibitors

    Copyright

    © © All Rights Reserved

    Available Formats

    DOC, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    Enfuvirtide is a fusion inhibitor that interferes with HIV-1 entry into CD4 cells by inhibiting the fusion of viral and cellular membranes. It is a 36-amino-acid synthetic peptide administered through subcutaneous injections twice daily into the arm, thigh, or abdomen. Common adverse effects include hypersensitivity reactions and injection site discomfort, but it has an improved safety profile compared to other antiretrovirals since it does not act inside host cells and is metabolized to amino acids with no interactions with other medications.

    Copyright:

    © All Rights Reserved
    Download as DOC, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as doc, pdf, or txt
    19 views1 page

    Fusion Inhibitors

    Uploaded by

    Falaq2
    Enfuvirtide is a fusion inhibitor that interferes with HIV-1 entry into CD4 cells by inhibiting the fusion of viral and cellular membranes. It is a 36-amino-acid synthetic peptide administered through subcutaneous injections twice daily into the arm, thigh, or abdomen. Common adverse effects include hypersensitivity reactions and injection site discomfort, but it has an improved safety profile compared to other antiretrovirals since it does not act inside host cells and is metabolized to amino acids with no interactions with other medications.

    Copyright:

    © All Rights Reserved
    Download as DOC, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as doc, pdf, or txt
    of 1

    Fusion Inhibitors

    Enfuvirtide
    Mechanism of action
    Enfuvirtide interferes with entry of HIV-1 into CD4 cells by
    inhibiting fusion of viral and cellular membranes.
    Pharmacokinetics
    Enfuvirtide is a 36-amino-acid synthetic peptide administered
    twice daily by subcutaneous injections into the arm, thigh, or
    abdomen.
    Adverse effects
    Adverse effects include hypersensitivity reactions and
    injection site discomfort. Overall, enfuvirtide may have an
    improved safety profile compared with other antiretrovirals
    because it does not exert its effects inside host cells. Because
    the drug is metabolized to individual amino acids, there
    are no interactions with other medications or with the P450
    hepatic enzymes. Adverse effects are primarily gastrointestinal
    (diarrhea, nausea

    You might also like