An action potential arrives at the presynaptic knob, opening calcium channels to allow calcium influx and triggering synaptic vesicles containing neurotransmitters to fuse with the presynaptic membrane, releasing neurotransmitters into the synaptic cleft. The neurotransmitters then diffuse across and bind to receptors on the postsynaptic membrane, opening ion channels that depolarize the postsynaptic membrane and may generate an action potential, while the neurotransmitters are broken down by enzymes and their products reabsorbed, with neurotransmitters repackaged into vesicles before the synaptic knob repolarizes.
An action potential arrives at the presynaptic knob, opening calcium channels to allow calcium influx and triggering synaptic vesicles containing neurotransmitters to fuse with the presynaptic membrane, releasing neurotransmitters into the synaptic cleft. The neurotransmitters then diffuse across and bind to receptors on the postsynaptic membrane, opening ion channels that depolarize the postsynaptic membrane and may generate an action potential, while the neurotransmitters are broken down by enzymes and their products reabsorbed, with neurotransmitters repackaged into vesicles before the synaptic knob repolarizes.
An action potential arrives at the presynaptic knob, opening calcium channels to allow calcium influx and triggering synaptic vesicles containing neurotransmitters to fuse with the presynaptic membrane, releasing neurotransmitters into the synaptic cleft. The neurotransmitters then diffuse across and bind to receptors on the postsynaptic membrane, opening ion channels that depolarize the postsynaptic membrane and may generate an action potential, while the neurotransmitters are broken down by enzymes and their products reabsorbed, with neurotransmitters repackaged into vesicles before the synaptic knob repolarizes.
An action potential arrives at the presynaptic knob, opening calcium channels to allow calcium influx and triggering synaptic vesicles containing neurotransmitters to fuse with the presynaptic membrane, releasing neurotransmitters into the synaptic cleft. The neurotransmitters then diffuse across and bind to receptors on the postsynaptic membrane, opening ion channels that depolarize the postsynaptic membrane and may generate an action potential, while the neurotransmitters are broken down by enzymes and their products reabsorbed, with neurotransmitters repackaged into vesicles before the synaptic knob repolarizes.