Diazepam

The half-life of diazepam is 4313 hours, but ranges from 40-100 hours if the
contribution from active metabolites is included. Diazepam is metabolized to
nordiazepam which is an active metabolite with a half-life of 40-99 hours.
Zolpidem
Zolpidem has a short elimination half-life (2.2 + 0.4 hours), which is reduced in
children (~ 1.4 hours) and increased in the elderly (~ 2.8 hours) and patients with
hepatic cirrhosis (~ 9.9 hours)
Diphenhydramine
The plasma half-life is 8.53.2 hours.
Gamma-hydroxybutyrate (GBH)
GHB is rapidly eliminated and has a half-life of 27 minutes (range 20-53 minutes).
Carisoprodol
The half-life of carisoprodol is approximately 100 minutes.
Cannabis
THC is highly lipid soluble, and plasma and urinary elimination half-lives are best
estimated at 3-4 days, where the rate-limiting step is the slow redistribution to
plasma of THC sequestered in the tissues.
Morphine
Morphine has a short half-life of 1.5 - 7 hours.
Close to 90% of a single morphine dose is eliminated in the 72 hours urine.
Heroin
Heroin has an extremely rapid half-life of 2-6 minutes.
Methadone
The half-life of (R,S)-methadone is 15-60 hours, and 10-40 hours for (R)methadone.

Sumber: National Highway Traffic Safety Administration (www.nhtsa.gov)

Barbiturates

Amobarbital: half life is 15-40 hours (dose dependent).

Butalbital: half life is 35-88 hours.
Pentobarbital: half life is 35-88 hours
Phenobarbital: half life of 2-6 days.
Secobarbital: half life is 22-29 hours

Thiopental: half life for this drug is 6-46 hours.