1) BrCA gene- function +mutations +risks

BRCA1 is a human gene and produces a protein called BRCA1.

BRCA1 is part of a complex that repairs double-strand breaks in DNA. The
strands of the DNA double helix are continuously breaking as they incur
damage.
A womans lifetime risk of developing breast and/or ovarian cancer is greatly
increased if she inherits a harmful mutation in BRCA1 or BRCA2.
Breast cancer: About 12 percent of women in the general population will
develop breast cancer sometime during their lives (4). By contrast, according
to the most recent estimates, 55 to 65 percent of women who inherit a
harmful BRCA1 mutation and around 45 percent of women who inherit a
harmful BRCA2 mutation will develop breast cancer by age 70 years (5, 6).
Ovarian cancer: About 1.4 percent of women in the general population will
develop ovarian cancer sometime during their lives (4). By contrast,
according to the most recent estimates, 39 percent of women who inherit a
harmful BRCA1 mutation (5, 6) and 11 to 17 percent of women who inherit a
harmful BRCA2 mutation will develop ovarian cancer by age 70 years (5, 6).
2) Pathophysiology of breast cancer
3) Pathophysiology of ovarian cancer
4) Treatments of both
Breast cancer:
5) Presymptomatic testing
6) Epidemiology (idiopathic) and risk factors