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Obtain sampling frame

Assessment

Contact eligible participants

Administer
lifestyle questionnaire

Administer
nutrition
assessment

Take urine &


blood sample

Genotyping

Metabolomics
profiling

Obtain
consent

Screening
for
cognitive
function

no

Refer to geriatric psychiatrists

eligible

Baseline
assessment

Data processing

Followup
screening
pass?

no

Confirm
by
geriatric
psychiatrists

yes
2 years

Repeated
assessment

End of study

no

yes

Confirmed
case

Take urine &


blood sample only

Input all the


variables named
KV,MVA,T,dim,range,group,cand,ITERATIONS

Contact eligible participants

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