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Alat dan Bahan

Alat :
1. HPLC Agilent 1200
2. Ultra sonic
3. Membran filter berukuran 0,2 m
4. Gelas ukur 1000 mL dan 500 mL
5. Mikropipet
6. Labu ukur 10 mL dan 100 mL
7. Neraca analisis
8. Corong
9. Pompa vakum
10. Syringe injector
11. Vial
Bahan
1.
2.
3.
4.
5.

Paracetamol syrup
Paracetamol tablet
Paracetamol standar
Metanol
Aqua bidest

Hasil pengamatan
1. Sampel paracetamol tablet
Kadar zat aktif PCT :
(%)

AUC sampel x pengenceran sampel x bobot baku


AUC baku x pengenceransampel x bobot sampel

20564225 x 200 x 0,05 gram


30608201 x 100 x 0,1
2 05642250
306082010

X 99,98%

0,67185 X 99,98%
67,17%
2. Sampel paracetamol syrup

X 99,98%

X KBB

Bobot sampel syrup :

volume yang dipipet


volume dalam etiket
1 mL
5 mL

X kadar PCT dalam etiket

X 120 mg

24 mg
AUC sampel x pengenceran sampel x bobot baku
Kadar zat aktif PCT : AUC baku x pengenceransampel x bobot sampel
(%)

56605696 x 2500 x 0,05


30608201 x 100 x 0,024
7075712000
73459682,4
96,321 X 99,98%
9630,17%

X 99,98%

X 99,98%

X KBB

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