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    Clubbing: First Described by Hippocrates About 2500yrs Ago, Hence Also Called As Hippocratic Finger

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    Dharmendra Khatri
    Clubbing, also known as Hippocratic finger, is a condition characterized by thickening of the tissues at the base of the fingernails and toenails such that the normal angle between the nail and digit is filled in. It is caused by increased levels of vascular endothelial growth factor which stimulates blood vessel growth and tissue proliferation in the fingers and toes. Common causes include lung diseases like bronchitis and lung cancer, as well as liver disease. Clubbing is graded based on the degree of nail bed fluctuation and curvature, ranging from nail bed fluctuation alone to a parrot-beak appearance of the fingernails.

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    Clubbing: First Described by Hippocrates About 2500yrs Ago, Hence Also Called As Hippocratic Finger

    Uploaded by

    Dharmendra Khatri
    46 views9 pages
    Clubbing, also known as Hippocratic finger, is a condition characterized by thickening of the tissues at the base of the fingernails and toenails such that the normal angle between the nail and digit is filled in. It is caused by increased levels of vascular endothelial growth factor which stimulates blood vessel growth and tissue proliferation in the fingers and toes. Common causes include lung diseases like bronchitis and lung cancer, as well as liver disease. Clubbing is graded based on the degree of nail bed fluctuation and curvature, ranging from nail bed fluctuation alone to a parrot-beak appearance of the fingernails.

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    Clubbing, also known as Hippocratic finger, is a condition characterized by thickening of the tissues at the base of the fingernails and toenails such that the normal angle between the nail and digit is filled in. It is caused by increased levels of vascular endothelial growth factor which stimulates blood vessel growth and tissue proliferation in the fingers and toes. Common causes include lung diseases like bronchitis and lung cancer, as well as liver disease. Clubbing is graded based on the degree of nail bed fluctuation and curvature, ranging from nail bed fluctuation alone to a parrot-beak appearance of the fingernails.

    Copyright:

    © All Rights Reserved
    Download as PPT, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as ppt, pdf, or txt
    46 views9 pages

    Clubbing: First Described by Hippocrates About 2500yrs Ago, Hence Also Called As Hippocratic Finger

    Uploaded by

    Dharmendra Khatri
    Clubbing, also known as Hippocratic finger, is a condition characterized by thickening of the tissues at the base of the fingernails and toenails such that the normal angle between the nail and digit is filled in. It is caused by increased levels of vascular endothelial growth factor which stimulates blood vessel growth and tissue proliferation in the fingers and toes. Common causes include lung diseases like bronchitis and lung cancer, as well as liver disease. Clubbing is graded based on the degree of nail bed fluctuation and curvature, ranging from nail bed fluctuation alone to a parrot-beak appearance of the fingernails.

    Copyright:

    © All Rights Reserved
    Download as PPT, PDF, TXT or read online from Scribd
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    of 9

    CLUBBING

    First described by Hippocrates


    about 2500yrs ago, hence
    also called as Hippocratic
    finger
    ABHIJIT SAMAL
    080201386

    DEFINITION
    Thickening of the tissues at the base
    of the finger and toe nails such that
    the normal angle between the nail &
    the digit is filled in.

    Pathophysiology
    VEGF is the key entity, platelet
    derived growth factor stimulated by
    hypoxia and produced in diverse
    malignancies.
    VEGF induces vascular hyperplasia,
    edema, and fibroblast or osteoblast
    proliferation at peripheral levels in
    nails

    CAUSES
    thoracic & non-thoracic
    THORACIC causes: bronchitis, empyema, lung
    abscess, cystic
    fibrosis, Lung Ca, Esophageal
    Ca,
    mesothelioma, Bac. Endocarditis.
    Interstitial lung disease: asbestosis,
    fibrosing alveolitis.
    Vascular causes: AV malformations,
    Cyanotic heart disease.

    Non-thoracic causes: Hepatic cirrhosis,


    Ulcerative colitis,
    Crohns
    disease.

    Criteria
    Loss of normal angle between nail
    and nail bed.
    Inc. Nail bed fluctuation
    Inc. nail bed curvature in the later
    stages
    Inc. bulk of soft tissue over the
    terminal phalanges

    Grades of clubbing
    Grade 1: Nail bed fluctuation
    Grade 2: Obliteration of Lovibond
    angle
    Grade 3: Parrot beaking
    Grade 4: Hypertrophic osteoarthropathy(HOA)

    Parrot beak app.


    Drumstick appearance

    Hypertrophic Osteoarthropathy
    Earlier known as hypertrophic
    pulmonary osteo-arthropathy(HPOA)
    Syndrome of clubbing of the digits,
    periostitis of the long bones and
    arthritis.
    Primary: occurs w/o any underlying
    cause and is familial
    Secondary: pulmonary, cardiac,
    hepatic, intestinal disease.

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