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Pathophysiology of peptic ulcer disease

Precipitating factor:
Predisposing factor:
Age Stress
gender Irritating food (spicy food and caffeinated
beverage)
Lifestyle
Occupation(driver)

Edematouse mucus
S/sx: membrane

Dull knowing skin or a burning sensation in a Damage mucosal barrier


midepigastrium or in the back. Hyperemic mucus membrane
Abdominal discomfort. (congested with fluid and
Headache blood).
Nausea
Anorexia
Vomiting Superficial erosion
hiccupping
Secretion of scanty amount of
gastric juice, containing very
little acid but much mucus.

Bleeding
Mucosal ulceration
Melena Insufficient secretion of mucus to act
Diarrhea
as a barrier against gastric acid.
Belching sour taste in the mouth
Nausea
Vomiting after eating.
ulcer

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