Osteoporosis

Antonius Permadi dr Mkes SpOT

Definition
Decrease of Bone Mass Density
accompanied by increase of fracture

Definition (WHO)
BMD Measure (Bone mineral density) 2 SD

Physiologic Bone Mass

Patophysiology

Patophysiology
The mechanism involving two type of cells :
Osteoclast
Osteoblast

Substances influences

Risk factor
Un-modified factor
Modified factor

Un-modified factor
Genetic ( caucasoid dan asia >>)
Family history
Early menopause period
Histerectomy / Oovorectomy procedure

Which one is vulnerable to get

Osteoporosis ?

Modified Factor
Life Style
L

Examination
X Ray
Laboratory exam (Calcium serum and
Urine, Osteocalcin)
USG
Bone densitometry

Bone Densitometry
The most sensitive to detect
osteoporosis

Prevention
Sport Activity
Weight bearing Sport

Prevention
Calcium
supplement

Depend on age
< 40 y.o : 800 - 1000 mg/day
> 40 y.o : 1000 -1500 mg/da

Treatment
Calcium supplement
Calcitriol supplement
Biphosphonate
Calcitonin supplement
Syntetic estrogen

Consultation to physician is
Mandatory

Terima Kasih