The document discusses key biopolymer network concepts including structural polymorphism in acto-myosin networks, the actin cortex as the thin cross-linked actin network just inside the cell membrane that controls cell shape through myosin motor contractile forces, gelation or assembly dynamics of cross-linked actin networks, and nucleation as the event when filament growth begins through polymerization such as via the Arp2/3 complex which is activated by nucleation promoting factors like Wasp.
The document discusses key biopolymer network concepts including structural polymorphism in acto-myosin networks, the actin cortex as the thin cross-linked actin network just inside the cell membrane that controls cell shape through myosin motor contractile forces, gelation or assembly dynamics of cross-linked actin networks, and nucleation as the event when filament growth begins through polymerization such as via the Arp2/3 complex which is activated by nucleation promoting factors like Wasp.
The document discusses key biopolymer network concepts including structural polymorphism in acto-myosin networks, the actin cortex as the thin cross-linked actin network just inside the cell membrane that controls cell shape through myosin motor contractile forces, gelation or assembly dynamics of cross-linked actin networks, and nucleation as the event when filament growth begins through polymerization such as via the Arp2/3 complex which is activated by nucleation promoting factors like Wasp.
Structural Polymorphism: Polymorphism is the ability of a material to exist in different crystal structure. e.g a rich structural polymorphism of acto-myosin network is desirable Actin cortex: Actin cortex is the thin cross-linked network just behind the cell membrane. The myosin motor exerts contractile forces onto actin cortex. Actin cortex is a crucial element in controlling cell shape. Gelation dynamics: Same as assembly. For example, gelation (Assembly) dynamics of cross-linked F-actin networks. Nucleation: Nucleation is an event, by which the filament start growing by polymerising. For example, Arp2/3 (Arp=Actin related protein) nucleates actin polymerization in lamellipodia. Nucleation promoting factors such as Wasp activates Arp2/3 complex.