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    This lab report summarizes key aspects of skeletal muscle structure and function. It describes how skeletal muscles contract with the aid of ATP to create movement. The sliding filament theory of muscle contraction is explained, involving the interaction of actin and myosin filaments. Experiments were conducted measuring the effects of ATP on muscle fiber length and width during contraction. Additional experiments measured muscle force and fatigue over time during continuous and repetitive gripping tasks. Results showed force decreasing more rapidly with repetitive gripping as ATP levels declined faster with continued exertion.

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    skeletalmusclestructure 1

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    This lab report summarizes key aspects of skeletal muscle structure and function. It describes how skeletal muscles contract with the aid of ATP to create movement. The sliding filament theory of muscle contraction is explained, involving the interaction of actin and myosin filaments. Experiments were conducted measuring the effects of ATP on muscle fiber length and width during contraction. Additional experiments measured muscle force and fatigue over time during continuous and repetitive gripping tasks. Results showed force decreasing more rapidly with repetitive gripping as ATP levels declined faster with continued exertion.

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    65 views5 pages

    Skeletal Muscle Lab Report

    Uploaded by

    api-296603992
    This lab report summarizes key aspects of skeletal muscle structure and function. It describes how skeletal muscles contract with the aid of ATP to create movement. The sliding filament theory of muscle contraction is explained, involving the interaction of actin and myosin filaments. Experiments were conducted measuring the effects of ATP on muscle fiber length and width during contraction. Additional experiments measured muscle force and fatigue over time during continuous and repetitive gripping tasks. Results showed force decreasing more rapidly with repetitive gripping as ATP levels declined faster with continued exertion.

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    SerenaVargas

    SkeletalMuscleLabReport
    SkeletalmusclescreatemovementbycontractingwiththeaidofATPthatthebodyproduces.
    TheFlemishPhysician,AndreasVesaliusin1543contributedtoskeletalmusclestudiesanddata
    withover200anatomicalillustrationsofskeletalmuscles.Musclecontractionisbasedona
    slidingfilamenttheorydevelopedbyfourpeople,AndrewF.Huxley,RolfNiedergerke,Hugh
    Huxley,andJeanHansonin1954.Tension,force,lengthandwidtharemeasureablevariablesof
    musclecontraction.AngeloMossoresearchedmusclefatigueandmusclefibersinthelate
    1800sandhediscoveredthatmusclefatiguehasanimpactonthemusclemobility.The
    followinglabswillbeaddressingskeletalmusclestructure,contractionandfatigueresearch.

    SkeletalMuscleStructure

    Figure1:ASkeletalMuscle
    Inthispictureisadetailedskeletalmusclewhicheachpartlabeled.Inthispicturetherearethe
    proteinsandthecellsfoundinthemuscle.Askeletalmuscleconsistsofavarietyoftissues,
    whichincludethelayersofconnectivetissue.Fasciacoverstheoutsideofthemuscle.The
    epimysiumisknownastheconnectivetissuethatsurroundstheskeletalmuscle.Theperimysium
    istheconnectivetissuethatstretchesfromtheepimysiumandunconnectsthemuscletissueinto
    sectionsthataresmaller.Insidethesesectionsarebundlesthatcontainskeletalmusclefibers
    whichareknownasfascicles.Everymusclefiberthatisinsideafasciclelieswithinalayerof
    connectivetissueintheconfigurationofacoveringthatisthin,knownasendomysium.

    Myofibrilsplayanessentialroleinthemechanismofmusclecontraction.Myofibrilsare
    consistedoftwoproteinfilaments.Thickfilamentsarecomposedoftheproteinmyosin.Thin
    filamentsarecomposedmainlyoftheproteinactin.

    MuscleContraction

    MuscularFiber
    Lengthsinmm

    BeforeATP
    Length

    AfterATP
    Length

    BeforeATP
    Width

    AfterATP
    Width

    80mm

    60mm

    15mm

    20mm

    100mm

    110mm

    23mm

    25mm

    47mm

    40mm

    15mm

    20mm

    75mm

    70mm

    14mm

    20mm

    Average

    75.5mm

    70mm

    16.75mm

    21.25

    %Contraction

    7%

    27%


    Forthislab,mylabpartnersandIusedaverysmallstripofrabbitskeletalmuscleandexamined
    itsreactionastheATPwasappliedtothemusclefilament.WhenmypartnersandIputadropof
    ATPonthemuscle,weseenithaveareactionofmovingbackandforth.Thedifferences
    betweenthetwopicturesisthatintheafterpicture,thefibersthatareinthepicturebecome
    wider,aswellasshorter.Thereasoningforthischangeisbecauseoftheslidingfilamenttheory.
    Whenthereisrisingoftheconcentrationofcalciumion,bindingsitesonactinfilamentsopen,
    andmyosinheadsattach,formingcrossingbridges.Oncethathappens,thecrossbridgesthan
    springfromtheirpositionandpullactinfilaments.Afterthat,theATPbindstothecrossbridge
    andduringthatprocessitreleasesitselffromtheactinfilament.AslongasthereisATPand
    calciumionspresent,thecyclewillcontinueon.

    Table1ContinuousGrip

    TimeInterval

    MaximumForce(N)

    MaximumForce(N)

    010s

    179.9

    2030s

    120.3

    59.6

    4050s

    127.3

    6070s

    135.2

    7.9

    8090s

    94.9

    40.3

    RepetitiveGripTable2

    TimeInterval

    MaximumForce(N)

    MaximumForce(N)

    010s

    120.2

    2030s

    144.7

    24.5

    4050s

    157.1

    12.4

    6070s

    95.8

    61.3

    8090s

    105.4

    9.6


    Inthesetrialsitwasclearthatonmycontinuousgripeffort,asthesecondsincreased,my
    maximumforcelessened.Intherepetitivegripeffort,myfatiguecameonmuchquicker.The
    causeofthisisbecausetheATPranoutofmymusclesfasterwhenIcontinuedtogripandgrip.

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