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Creeping Fat in Crohn's Disease

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Creeping fat is a characteristic feature of Crohn's disease where adipose tissue grows outside the intestinal wall and into surrounding tissues. Adipocytokines are proteins secreted by adipose tissue that are emerging as playing a role in intestinal and mesenteric diseases like Crohn's. A 2005 study examined the mechanisms by which visceral adipose tissue and adipocytokines may contribute to diseases of the intestines and surrounding mesentery.

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Pathological demonstration.

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Creeping Fat in Crohn's Disease

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FIGURE 2 Characteristic features of creeping fat in Crohn's disease

Schaffler A et al. (2005) Mechanisms of Disease: adipocytokinesand visceral adipose tissue-emerging role
in intestinal and mesenteric diseases
Nat Clin Pract Gastroenterol Hepatol 2: 103111 doi:10.1038/ncpgasthep0090

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