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Week 3 JointInflammatoryDisease - 27 Agustus 2012
Week 3 JointInflammatoryDisease - 27 Agustus 2012
JOINT DISEASES
BY DARTI WIBISONO
1/10/16
created by darti
INFLAMMATORY JOINT
DISEASES
RHEUMATOID
ARTHRITIS
OSTEOARTHRITIS
SYNOVITIS
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created by darti
GOUT
BURSITIS
ARTHRITIS
SYNOVITIS
BURSITIS
Rheumatoid nodles
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BURSITIS
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Inflammation of
Tendonitis/bursitis
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OSTEOARTHRITIS
DEGENERATIVE
DEGENERATIVE ARTHRITIS
ARTHRITIS
DEGENERATIVE
DEGENERATIVE JOINT
JOINT DISEASE
DISEASE
1/10/16
created by darti
DD
RA is a systemic disease,
which means it can affect other organs in
the body
GOUT is a disorder of purine metabolism.
There is hyperuricemia (serum uric acid > 7
mg/dl)
1/10/16
created by darti
OSTEOARTHRITI
S
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-SCLEROTIC
-OSTEOPOROTIC
-CYSTIC LESION
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RHEUMATOID
ARTHRITIS
The main target tissue is the synovial
membrane of joints(synovitis/polyarthritis)
Pathology,
Early
Intermediate
Late
1/10/16
created by darti
SYNOVITIS
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PANNUS
It is an ingrowth
of
synovial
material into a
joint
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RHEUMATOID
NODULE
The Histological appearance :
Central area
of well
demarcated
fibrinoid
necrosis
Palisade of histiocytes
Well
collagenised
granulation tissue
Bamboospine :
Bony union on
the priphery of
the
intervertebral
disc
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Vision loss
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Giant
Cell(Temporal)Arteriti
s
A biopsy is recommended.
The procedure is performed
with local anesthesia.
This test allows doctors to
definitively diagnose
temporal arteritis.
1/10/16
created by darti
1/10/16
created by darti
Obliterate
d
lumen
GOUT
The arthritis of gout begins as acute
inflammatory process affecting
ussually a great toe
microscopi
c
Urate crystsls
deposited
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MUSCLE/LIGAMENT ATROPHY
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created by darti
Atrophy of skeletal
muscle.
There are two possible
causes
for the atrophy:
1) disuse
2) loss of nerve supply.
The presence of cross
striations indicate that this is
striated muscle and the
peripheral location of the
nuclei distinguishes it from
cardiac muscle.
1/10/16
created by darti