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INFLAMMATORY

JOINT DISEASES

BY DARTI WIBISONO

1/10/16

created by darti

INFLAMMATORY JOINT
DISEASES

RHEUMATOID
ARTHRITIS

OSTEOARTHRITIS

SYNOVITIS

1/10/16

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GOUT

BURSITIS

ARTHRITIS
SYNOVITIS
BURSITIS

Rheumatoid nodles
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BURSITIS

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Inflammation of
Tendonitis/bursitis

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OSTEOARTHRITIS
DEGENERATIVE
DEGENERATIVE ARTHRITIS
ARTHRITIS
DEGENERATIVE
DEGENERATIVE JOINT
JOINT DISEASE
DISEASE

1/10/16

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DD

RA is a systemic disease,
which means it can affect other organs in
the body
GOUT is a disorder of purine metabolism.
There is hyperuricemia (serum uric acid > 7
mg/dl)

1/10/16

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OSTEOARTHRITI
S

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THE SUBCHONDRAL BONE


REACTION IN OA
Pract.:
-Ganglion
cysts
-Bursitis

-SCLEROTIC
-OSTEOPOROTIC
-CYSTIC LESION

1/10/16

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RHEUMATOID
ARTHRITIS
The main target tissue is the synovial

membrane of joints(synovitis/polyarthritis)
Pathology,
Early

An active chronic inflammation of the synovial


membrane.

Intermediate

Destruction of cartilage by enzymatic action and


granulation tissue spreading over the articular
surface (PANNUS)

Late

1/10/16

Severe distorted joint

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SYNOVITIS

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PANNUS

It is an ingrowth
of
synovial
material into a
joint

1/10/16

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RHEUMATOID
NODULE
The Histological appearance :
Central area
of well
demarcated
fibrinoid
necrosis
Palisade of histiocytes
Well
collagenised
granulation tissue
Bamboospine :
Bony union on
the priphery of
the
intervertebral
disc
1/10/16

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Giant Cell arteritis


Temporal arteritis
An inflammatory condition
affecting medium sized blood
vessels that supply head,eyes
and optic nerves

Vision loss

1/10/16

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Giant
Cell(Temporal)Arteriti
s
A biopsy is recommended.
The procedure is performed
with local anesthesia.
This test allows doctors to
definitively diagnose
temporal arteritis.

1/10/16

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Giant Cell Arteritis,


Temporal arteritis
Granulomatous arteritis
Systemic Necrotizing
Vasculitis

1/10/16

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Obliterate
d
lumen

GOUT
The arthritis of gout begins as acute
inflammatory process affecting
ussually a great toe

microscopi
c
Urate crystsls
deposited
1/10/16

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MUSCLE/LIGAMENT ATROPHY

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Atrophy of skeletal
muscle.
There are two possible
causes
for the atrophy:
1) disuse
2) loss of nerve supply.
The presence of cross
striations indicate that this is
striated muscle and the
peripheral location of the
nuclei distinguishes it from
cardiac muscle.
1/10/16

created by darti

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