Diuretics work by targeting sites in the kidneys to increase urine output and reduce fluid retention. The main classes are thiazides, loop diuretics, and potassium-retaining diuretics, which have different mechanisms and side effect profiles. Diuretics are used to treat edema caused by conditions like heart failure or liver disease, hypertension, and other fluid-related issues. Proper administration is important to balance their effects on electrolytes and acid-base levels while reducing excess fluid. Less common diuretic classes include osmotics and carbonic anhydrase inhibitors.
Diuretics work by targeting sites in the kidneys to increase urine output and reduce fluid retention. The main classes are thiazides, loop diuretics, and potassium-retaining diuretics, which have different mechanisms and side effect profiles. Diuretics are used to treat edema caused by conditions like heart failure or liver disease, hypertension, and other fluid-related issues. Proper administration is important to balance their effects on electrolytes and acid-base levels while reducing excess fluid. Less common diuretic classes include osmotics and carbonic anhydrase inhibitors.
Diuretics work by targeting sites in the kidneys to increase urine output and reduce fluid retention. The main classes are thiazides, loop diuretics, and potassium-retaining diuretics, which have different mechanisms and side effect profiles. Diuretics are used to treat edema caused by conditions like heart failure or liver disease, hypertension, and other fluid-related issues. Proper administration is important to balance their effects on electrolytes and acid-base levels while reducing excess fluid. Less common diuretic classes include osmotics and carbonic anhydrase inhibitors.
Diuretics work by targeting sites in the kidneys to increase urine output and reduce fluid retention. The main classes are thiazides, loop diuretics, and potassium-retaining diuretics, which have different mechanisms and side effect profiles. Diuretics are used to treat edema caused by conditions like heart failure or liver disease, hypertension, and other fluid-related issues. Proper administration is important to balance their effects on electrolytes and acid-base levels while reducing excess fluid. Less common diuretic classes include osmotics and carbonic anhydrase inhibitors.
Members Mechanism of action: 1) Site of action of the diuretic 2) How the diuretic reaches its site of action 3) The main diuretic target a. Thiazides b. Loop c. K-retaining 4) Additional non-diuretic actions Adverse effects: 1) Effects on blood chemistry: a. Water b. Electrolytes: i. Sodium ii. Potassium & Magnesium iii. Calcium c. Acid base balance d. Glucose e. Uric acid 2) General adverse effects 3) Special adverse effects Indications: 1) Oedema a. Heart failure and acute pulmonary edema b. Hepatic edema c. Nephrotic edema d. Acute renal failure e. Refractory edema f. Other types of edema Practical points about edema 2) Hypertension 3) Additional indications Administration Rare Diuretics: 1) Osmotic diuretics 2) Carbonic Anhydrase Inhibitors