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    Fine Needle Aspiration Cytology (Biopsy)

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    delviastri_widyana
    Fine needle aspiration cytology involves using thin needles to aspirate cells or tissue fragments from suspicious masses or abnormalities detected by imaging. It is a relatively non-invasive procedure compared to surgical biopsy and allows for early diagnosis. Samples are smeared and examined under a microscope to analyze cellular characteristics and make a diagnosis. Potential complications are rare and minor. Fine needle aspiration cytology is an accurate, fast, and less painful alternative to surgical biopsy.

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    Fine Needle Aspiration Cytology (Biopsy)

    Uploaded by

    delviastri_widyana
    34 views35 pages
    Fine needle aspiration cytology involves using thin needles to aspirate cells or tissue fragments from suspicious masses or abnormalities detected by imaging. It is a relatively non-invasive procedure compared to surgical biopsy and allows for early diagnosis. Samples are smeared and examined under a microscope to analyze cellular characteristics and make a diagnosis. Potential complications are rare and minor. Fine needle aspiration cytology is an accurate, fast, and less painful alternative to surgical biopsy.

    Original Description:

    FNAC PDL

    Original Title

    FNAC PDL

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    Fine needle aspiration cytology involves using thin needles to aspirate cells or tissue fragments from suspicious masses or abnormalities detected by imaging. It is a relatively non-invasive procedure compared to surgical biopsy and allows for early diagnosis. Samples are smeared and examined under a microscope to analyze cellular characteristics and make a diagnosis. Potential complications are rare and minor. Fine needle aspiration cytology is an accurate, fast, and less painful alternative to surgical biopsy.

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    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pptx, pdf, or txt
    34 views35 pages

    Fine Needle Aspiration Cytology (Biopsy)

    Uploaded by

    delviastri_widyana
    Fine needle aspiration cytology involves using thin needles to aspirate cells or tissue fragments from suspicious masses or abnormalities detected by imaging. It is a relatively non-invasive procedure compared to surgical biopsy and allows for early diagnosis. Samples are smeared and examined under a microscope to analyze cellular characteristics and make a diagnosis. Potential complications are rare and minor. Fine needle aspiration cytology is an accurate, fast, and less painful alternative to surgical biopsy.

    Copyright:

    © All Rights Reserved
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    of 35

    Fine Needle

    Aspiration Cytology
    (Biopsy)

    FNAC - definition
    Aspiration

    of cells/ tissue fragments using fine


    needles ( 22 , 23, 25 G) ; external diameter
    0.6 to 1.0 mm
    1.5 inches long needle ( radiologists use
    longer needles)
    Diagnostic materials in the needle and not in
    the syringe even in cystic lesions

    Fine needle aspiration biopsies are often


    performed when a suspicious mass is found, for
    example a breast lump/mass or enlarged lymph
    node, or if an abnormality is detected on an
    imaging test such as x-ray, ultrasound or
    mammography.

    Fine needle aspiration is a relatively noninvasive, less painful and quicker method when
    compared to other methods of tissue sampling
    such as surgical biopsy.

    A cyst aspiration can also be achieved with a


    FNA, where the fluid is drained from a cyst with
    no need for analysis.

    Who should do FNA?


    Clinicians
    Cytotechnologists
    Radiologists
    Pathologists

    ne who examines the patients , does the asp


    es the smears, interprets the cytology
    best one to do FNA PATHOLOGIST

    Current status
    Palpable

    lesions
    Outpatients , in- patients
    Thyroid , breast, lymph nodes,
    salivary glands , soft tissue lumps...
    Lung, intra-abdominal and
    retroperitoneal by radiologic imaging
    : CT, ultrasound, flouroscopy

    Complications

    Needle trauma
    granulation tissue

    formation
    granuloma
    formation
    Sarcoma like
    changes
    Needle linear tract
    haemorrhage
    tissue necrosis

    Needle track
    seeding - testicular
    tm, chondrosar
    Hematoma
    Pain
    Pneumothorax???

    ADVANTAGES
    Fast

    - early diagnosis
    Less pain, less trauma
    No anaesthesia
    Acceptable by patients and doctors
    Accurate

    How to interpret?
    Aspiration

    materials eg colloid,
    blood, mucus?
    Cellular yield vs acellular yield
    Smear pattern - 3 dimensional balls
    vs flat monolayered sheet os cells
    Cohesiveness vs discreet cells
    Cell morphometry

    Adjunct tools
    Cell

    blocks
    Histochemistry
    Immunohistochemistry
    Electron microscopy
    Flow cytometry
    Immuno electron microscopy
    Molecular pathology -In situ
    hybridization, PCR etc

    Adjunct tools
    IHC
    cytology

    Histo - thyroid

    Cell block

    45 yr old woman with


    lytic bone lesion

    Histo -bone

    20

    21

    29

    Maneuver The Target

    30

    Cytology vs Histology

    apillary carcinoma of thyroid - follicular varian

    Cytology vs Histology - 2

    Granular Cell Myoblastoma

    Lumbar puncture
    Aspiration of liver cyst

    Iliac crest puncture of bone marrow

    Terima Kasih

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