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General Questions About West Nile Virus
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What is West Nile virus?

How do people get infected with West Nile virus?

Who is at risk for infection with West Nile virus?

Is there a vaccine available to protect people from West Nile virus?

How soon do people get sick after getting bitten by an infected mosquito?

What are the symptoms of West Nile virus disease?

Who is at risk for serious illness if infected with West Nile virus?

What should I do if I think a family member might have West Nile virus disease?

How is West Nile virus disease diagnosed?

What is the treatment for West Nile virus disease?

When do most cases of West Nile virus disease occur?

Where do most cases of West Nile virus disease occur?

How can people reduce the chance of getting infected?

Why do my state health department and CDC sometimes report different numbers of West
Nile virus cases?

What is West Nile virus?

West Nile virus is an arthropod-borne virus (arbovirus) most commonly spread by infected
mosquitoes. West Nile virus can cause febrile illness, encephalitis (inflammation of the brain) or
meningitis (inflammation of the lining of the brain and spinal cord).
West Nile virus transmission has been documented in Europe and the Middle East, Africa, India,
parts of Asia, and Australia. It was first detected in North America in 1999, and has since spread
across the continental United States and Canada.

How do people get infected with West Nile virus?

Most people get infected with West Nile virus by the bite of an infected mosquito. Mosquitoes
become infected when they feed on infected birds. Infected mosquitoes can then spread the virus to
humans and other animals.
In a very small number of cases, West Nile virus has been spread through blood transfusions, organ
transplants, and from mother to baby during pregnancy, delivery, or breastfeeding.
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Who is at risk for infection with West Nile virus?

Anyone living in an area where West Nile virus is present in mosquitoes can get infected. West Nile
virus has been detected in all lower 48 states (not in Hawaii or Alaska). Outbreaks have been
occurring every summer since 1999. The risk of infection is highest for people who work outside or
participate in outdoor activities because of greater exposure to mosquitoes.
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Is there a vaccine available to protect people from West Nile

virus?
No. Currently there is no West Nile virus vaccine available for people. Many scientists are working on
this issue, and there is hope that a vaccine will become available in the future.
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How soon do people get sick after getting bitten by an infected

mosquito?

The incubation period is usually 2 to 6 days but ranges from 2 to 14 days. This period can be longer
in people with certain medical conditions that affect the immune system.
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What are the symptoms of West Nile virus disease?

No symptoms in most people. Most people (70-80%) who become infected with West Nile virus do
not develop any symptoms.
Febrile illness in some people. About 1 in 5 people who are infected will develop a fever with other
symptoms such as headache, body aches, joint pains, vomiting, diarrhea, or rash. Most people with
this type of West Nile virus disease recover completely, but fatigue and weakness can last for weeks
or months.
Severe symptoms in a few people. Less than 1% of people who are infected will develop a serious
neurologic illness such as encephalitis or meningitis (inflammation of the brain or surrounding
tissues). The symptoms of neurologic illness can include headache, high fever, neck stiffness,
disorientation, coma, tremors, seizures, or paralysis.
Recovery from severe disease may take several weeks or months. Some of the neurologic effects
may be permanent. About 10 percent of people who develop neurologic infection due to West Nile
virus will die.
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Who is at risk for serious illness if infected with West Nile virus?
Serious illness can occur in people of any age. However, people over 60 years of age are at the
greatest risk for severe disease. People with certain medical conditions, such as cancer, diabetes,
hypertension, kidney disease, and people who have received organ transplants, are also at greater
risk for serious illness.
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What should I do if I think a family member might have West

Nile virus disease?
Consult a healthcare provider for evaluation and diagnosis.
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How is West Nile virus disease diagnosed?

Diagnosis is based on a combination of clinical signs and symptoms and specialized laboratory tests
of blood or spinal fluid. These tests typically detect antibodies that the immune system makes
against the viral infection.
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What is the treatment for West Nile virus disease?

There are no medications to treat or vaccines to prevent West Nile virus infection. Over-the-counter
pain relievers can be used to reduce fever and relieve some symptoms.
People with milder symptoms typically recover on their own, although some symptoms may last for
several weeks.
In more severe cases, patients often need to be hospitalized to receive supportive treatment, such
as intravenous fluids, pain medication, and nursing care.
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When do most cases of West Nile virus disease occur?

Most people are infected from June through September.
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Where do most cases of West Nile virus disease occur?

West Nile virus disease cases have been reported from all 48 lower states. The only states that have
not reported cases are Alaska and Hawaii. Seasonal outbreaks often occur in local areas that can
vary from year to year. The weather, numbers of birds that maintain the virus, numbers of
mosquitoes that spread the virus, and human behavior are all factors that can influence when and
where outbreaks occur.
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How can people reduce the chance of getting infected?

The most effective way to avoid West Nile virus disease is to prevent mosquito bites:

Use insect repellents when you go outdoors. Repellents containing DEET, picaridin, IR3535,
and some oil of lemon eucalyptus and para-menthane-diol products provide longer-lasting
protection.

Wear long sleeves and pants from dusk through dawn when many mosquitoes are most
active.

Install or repair screens on windows and doors. If you have it, use your air conditioning.

Help reduce the number of mosquitoes around your home. Empty standing water from
containers such as flowerpots, gutters, buckets, pool covers, pet water dishes, discarded tires,
and birdbaths.

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Why do my state health department and CDC sometimes report

different numbers of West Nile virus cases?
The CDC case count is based on the number of cases that have been reported by each state health
department to CDC. The CDC case count is updated once a week during the transmission season.
State health departments might update their counts more often.

Prevention & Control

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Fact Sheet: Mosquito Bite Prevention for the United States[PDF - 2 pages]
The most effective way to avoid West Nile virus disease is to prevent mosquito bites. Be aware of the
West Nile virus activity in your area and take action to protect yourself and your family.

Avoid Mosquito Bites

Use insect repellents when you go outdoors. Repellents containing DEET, picaridin,
IR3535, and some oil of lemon eucalyptus and para-menthane-diol products provide longerlasting protection. To optimize safety and effectiveness, repellents should be used according to
the label instructions.

More information about insect repellents can be found here.

When weather permits, wear long sleeves, long pants, and socks when
outdoors.Mosquitoes may bite through thin clothing, so spraying clothes with repellent
containing permethrin or another EPA-registered repellent will give extra protection. Don't apply
repellents containing permethrin directly to skin. Do not spray repellent on the skin under your
clothing.

Take extra care during peak mosquito biting hours. Take extra care to use repellent and
protective clothing from dusk to dawn or consider avoiding outdoor activities during these times.

Mosquito-Proof Your Home

Install or repair screens on windows and doors to keep mosquitoes outside. Use your air
conditioning, if you have it.

Help reduce the number of mosquitoes around your home by emptying standing water from
flowerpots, gutters, buckets, pool covers, pet water dishes, discarded tires, and birdbaths on a
regular basis.

Help Your Community West Nile Virus Surveillance and Control

Programs

Support your local community mosquito control programs. Mosquito control activities
are most often handled at the local level, such as through county or city government. The type of
mosquito control methods used by a program depends on the time of year, the type of
mosquitoes to be controlled, and the habitat structure. Methods can include elimination of
mosquito larval habitats, application of insecticides to kill mosquito larvae, or spraying
insecticides from trucks or aircraft to kill adult mosquitoes. Your local mosquito control program
can provide information about the type of products being used in your area. Check with your
local health department for more information. Contact information may be found in the blue
(government) pages of the phone book.

More information about mosquito control can be found here.

Resources for vector control professionals are located here.

Report dead birds to local authorities. Dead birds may be a sign that West Nile virus is
circulating between birds and the mosquitoes in an area. By reporting dead birds to state and
local health departments, you can play an important role in monitoring West Nile virus. State and
local agencies have different policies for collecting and testing birds, so check with your state
health department to find information about reporting dead birds in your area.

Additional Information about Insect Repellents

Protection against Mosquitoes, Ticks, & Other Insects & Arthropods (CDC)

National Pesticide Information Center

File Formats Help:

Symptoms & Treatment

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No symptoms in most people. Most people (70-80%) who become infected with West Nile virus do
not develop any symptoms.
Febrile illness in some people. About 1 in 5 people who are infected will develop a fever with other
symptoms such as headache, body aches, joint pains, vomiting, diarrhea, or rash. Most people with
this type of West Nile virus disease recover completely, but fatigue and weakness can last for weeks
or months.
Severe symptoms in a few people. Less than 1% of people who are infected will develop a serious
neurologic illness such as encephalitis or meningitis (inflammation of the brain or surrounding
tissues).

The symptoms of neurologic illness can include headache, high fever, neck stiffness,
disorientation, coma, tremors, seizures, or paralysis.

Serious illness can occur in people of any age. However, people over 60 years of age are at
the greatest risk for severe disease. People with certain medical conditions, such as cancer,
diabetes, hypertension, kidney disease, and people who have received organ transplants, are
also at greater risk for serious illness.

Recovery from severe disease may take several weeks or months. Some of the neurologic
effects may be permanent.

About 10 percent of people who develop neurologic infection due to West Nile virus will die.

Treatment

No vaccine or specific antiviral treatments for West Nile virus infection are available.

Over-the-counter pain relievers can be used to reduce fever and relieve some symptoms

In severe cases, patients often need to be hospitalized to receive supportive treatment, such
as intravenous fluids, pain medication, and nursing care.

More detailed information can be found on our page for health care providers.

Transmission
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West Nile virus is most commonly transmitted to humans by mosquitoes.

Additional routes of human infection have also been documented. It is important to note that these
methods of transmission represent a very small proportion of cases:

Blood transfusions

Organ transplants

Exposure in a laboratory setting

From mother to baby during pregnancy, delivery, or breastfeeding

West Nile virus is not transmitted:

From person-to-person or from animal-to-person through casual contact. Normal veterinary

infection control precautions should be followed when caring for a horse suspected to have
this or any viral infection.

From handling live or dead infected birds. You should avoid bare-handed contact when
handling any dead animal. If you are disposing of a dead bird, use gloves or double plastic
bags to place the carcass in a garbage can.

Through consuming infected birds or animals. In keeping with overall public health practice,
and due to the risk of known food-borne pathogens, always follow procedures for fully cooking
meat from either birds or mammals.

Transmission cycle

West Nile Virus Transmission Cycle[PDF - 1 page]