PKG 602.54 TO 55

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DEPARTMENT OF TECHNICAL EDUCATION

ANDHRA PRADESH
Name
Designation
Branch
Institute
Year
Subject
Subject code
Topic
Duration
Sub Topic
Teaching aids

: Y.Venkat Reddy
: Senior Lecturer
: Packaging Technology
: 002,J.N.Govt.Polytechnic, Hyd
: VI Semester
: Product Packaging
: Pkg 602
: Introduction to Aerosol Packaging
: 100 Minutes
: Aerosol Packaging Technology
: PPT, Visuals, Animations
Pkg 602.54 TO 55

Objectives
On competition of this period, you would be able to
know :
(1) Advantages of aerosols
(2) Disadvantages of aerosols
(3) Formulation of aerosols

Pkg 602.54 TO 55

Aerosols

Definition:

Aerosols are known as pressurised dosage forms and


packed in special pressurised aerosol containers.

Pkg 602.54 TO 55

Aerosol

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Aerosol Container

Fig: 18.9

Must be strong to withstand high pressure inside the


container
Made up of glass, plastic and metal
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Advantages
1.

Medicament can be delivers and directly to affected


area.

2.

Absence and air prevents oxidation.

3.

Hydrolysis is prevented.

4.

Sterility can be maintained.

5.

Application is easy.

6.

Fine mist is formed for inhalation purpose.

7.

Drug does not enter GIT- No degradation.


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Disadvantages
1.

Costly.

2.

Some propellants are toxic.


cooling effect may cause discomfort.

Classification and Aerosols


1.

Space sprays.

2.

Surface coats.

3.

Foams.
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Formulation
Consists of
1)

Propellant

2)

drug

Propellant:- develops pressure compressed gases like


CO2, N2, methane.
Fluoro carbons
Tricholoro fluoro methane
Dichloro Difluoro methane
Dichloro tetra fluoro methane
Difluoro - ethane
Pkg 602.54 TO 55

Formulation
Medicament may be solid or liquid
may be soluble in propellant or insoluble.

Additives: Solvents
Antioxidants.
Surface active agents.

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Types of Aerosol system

1.

Two-phase system

2.

Three phase system

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Parts of Aerosol system


1.

Container

2.

Valves

3.

Actuator

4.

Dip tubes

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Filling of Aerosols
Aerosols products can be filled in two ways:

Cold- fill process

Pressure -fill process

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Summary

In this period you learnt about:


Definition of aerosol.
Advantages & Disadvantages of aerosols.
The aerosol formulation.

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13

Quiz
prescribed dosage forms
1. Aerosols are ______________
Aerosols
2. Sterility can be maintained by _______

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14

Frequently Asked Questions

1.

Write the advantages & disadvantages of aerosols.

2.

Write about various parts of aerosols.

3.

Write about aerosols formulation.

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