When writing to different audiences I would consider the type of audience.
When I say type I mean age, gender, race, social class, etc. I feel as though all of these factors should influence what and how you write something. If, for example, you make a Prezi. You would want the Prezi to reach multiple audiences, or maybe just the audience that you are supposed to be presenting to. If you were presenting to a younger audience then you would use more modern pictures, videos and music. Also, you would probably use more slang words that we use today to help the audience understand and stay interested. If I was targeting an older audience I may use full words and not the music, videos, and images that I would use with the younger audiences.