Translocations

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t(9;12) c-abl

CML

t(8;14) c-myc

B-cell lymphoma

t(2;8) N-myc

Burkitt's lymphoma

t(2;8) c-myc

Burkitt's lymphoma

t(3;8) raf

Parotid gland tumor

t(6;14) myb

Carcinoma

t(3;8) mas

AML

t(9;22) abl and sis

CML

Translocations

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N-myc gene amplification

Neuroblastoma

neu gene amplification

Breast carcinoma

pRb

Retinoblastoma

WT

Wilms' tumor

NFI

Neurofibroma, sarcoma

FAP

Familial adenomatous
polyposis

p53

Breast, SCLC, cervical,

and bladder cancers

DCC

Colon cancer

Translocations

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t(2;6)

Biphenotypic leukemia

t(14;18) Bcl-2

Follicular lymphoma

t(11;14) Bcl-1

Mantle cell lymphoma

t(X;18)

Synovial sarcoma

t(2;5)

Anaplastic large cell

lymphoma

t(8;14) c-myc

Burkitt's lymphoma

t(9;22)

Philadelphia chromosome
CML and ALL

t(11;22)

Ewing's sarcoma

Translocations

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t(17;22)

Dermaofibrosarcoma
protuberans

t(5;17)

Acute promyeloctyic
leukemia

t(1;12)

AML

t(9;12)

CML, ALL

t(1;11)

Schizophrenia

t(12;16) & t(12;22) Myxoid liposarcoma

t(5;17)

Acute promyelocytic
leukemia

t(11;18)

MALT

Translocations

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Chromosome 17

NF1 "Vo n Re ckl i n g h a u s e n ' s Dz "

NF1 > NF2
In cr e a s e d r i s k o f Mo ya m o ya
In cr e a s e d r i s k o f 2 n d ca n ce r s
Li s ch n o d u l e s o n i r i s e s
O p ti c g l i o m a s

Chromosome 22

NF2
NF2
Bilateral acoustic neuromas