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  • Increase Pulmonary Vascular Markings: MITHA Y. - 108

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    Pratiara Syamir Fasa
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    The document summarizes the pathogenesis of drug abuse during pregnancy leading to patent ductus arteriosus in the newborn. Key points: 1) Amphetamines used by the mother can cross the placenta, increasing blood pressure and stimulating the release of neurotransmitters in the fetus. 2) This damages the inner wall of the ductus arteriosus, causing it to dilate and impairing its ability to close after birth. 3) The newborn then has a continuous murmur and other signs of patent ductus arteriosus, with blood shunting from the aorta to the pulmonary artery, overloading the lungs and impairing systemic perfusion.

    Original Description:

    naruto

    Original Title

    Patogenesis Naruto

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    The document summarizes the pathogenesis of drug abuse during pregnancy leading to patent ductus arteriosus in the newborn. Key points: 1) Amphetamines used by the mother can cross the placenta, increasing blood pressure and stimulating the release of neurotransmitters in the fetus. 2) This damages the inner wall of the ductus arteriosus, causing it to dilate and impairing its ability to close after birth. 3) The newborn then has a continuous murmur and other signs of patent ductus arteriosus, with blood shunting from the aorta to the pulmonary artery, overloading the lungs and impairing systemic perfusion.

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    © All Rights Reserved
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    30 views1 page

    Increase Pulmonary Vascular Markings: MITHA Y. - 108

    Uploaded by

    Pratiara Syamir Fasa
    The document summarizes the pathogenesis of drug abuse during pregnancy leading to patent ductus arteriosus in the newborn. Key points: 1) Amphetamines used by the mother can cross the placenta, increasing blood pressure and stimulating the release of neurotransmitters in the fetus. 2) This damages the inner wall of the ductus arteriosus, causing it to dilate and impairing its ability to close after birth. 3) The newborn then has a continuous murmur and other signs of patent ductus arteriosus, with blood shunting from the aorta to the pulmonary artery, overloading the lungs and impairing systemic perfusion.

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    © All Rights Reserved
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    of 1

    PATOGENESIS

    NARUTO
    IBU
    Saat kehamilan Trimester I
    Drug abuse ( AMPHETAMINES )

    Menembus sawar plasenta

    me TD ibu

    Fetus

    Mpengaruhi
    sirkulasi janin

    Mrangsang pelepasan NE,


    dopamin, serotonin
    Vasokonstriksi p.d.

    Merusak tunika
    intima duktus
    arteriosus janun

    Feedback (-)
    Dinding p.d melepas
    prostaglandin
    Vasodilator

    Diameter DA
    tlalu mbesar

    Increase pulmonary vascular markings

    PD
    A

    Saat lahir DA
    sulit menutup
    Dilatasi AP

    Terdengar
    mumur

    Aliran darah dari aorta ke arteri pulmonalis (AP)

    Volume darah ke paru-paru

    Darah ke sistemik <<<


    pe perfusi ke organ & perifer

    Saat
    sistolik
    mengeras

    Saat diastolik
    melemah

    Continuous
    murmur at
    the left
    infraclavicular area

    Ronkhi / pulmonary crackles (+)

    pe Fx paru u
    mengeluarkan
    debris
    Infeksi nafas
    berulang

    Vena pulmonalis

    Darah dari RV
    tertahan

    Vol. LA & LV
    P.
    hidrostatik
    > P. onkotik

    Murmur
    grade 4/6
    Systolic
    thrill in the
    upper left
    sernal
    border

    Tek. P. kapiler
    paru

    Ekstravasasi cairan ke
    rongga
    alveolar

    Edema paru

    Edema batang
    bronkus
    Rangsangan
    respon iritan di
    saluran nafas

    Ventilasi
    tganggu
    Kerja
    pernafas
    an

    Mek. kompensasi
    Hipertrofi
    LA & LV

    Beban volume
    jantung kanan
    tek. Vena cava
    inferior
    Kongesti hati

    Takipneu
    (orthopnoe )

    Hyperactive
    precordium

    kulit

    otot

    Respon
    simpatis

    pale

    ATP

    Stimulasi k.
    keringat

    Vasokonstri
    ksi arteriol
    di kepala

    Mek.
    anaerob
    As. Laktat

    hepatomegali
    pe
    distribusi
    panas
    (dingin )

    Shortness
    of breath

    Kontraksi
    LV

    kepala

    Chest
    precordial
    bulging

    Downward
    apex

    fatigue
    pe
    aktivitas

    Keringat dingin di
    dahi

    Menekan
    diafragma
    & lambung

    Refleks nafas

    anorexia

    batuk

    malnutrisi
    Poor
    weight gain

    MITHA Y. _108_

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