Professional Documents
Culture Documents
Skin Circulation
Skin Circulation
circulation
Learning Issues
Characteristic features
Triple response
Role in temperature regulation
Factors regulating cutaneous
circulation
General responses changing the
color of skin
Cutaneous (Skin)
circulation
Characteristics
Well innervated anastomotic
connections between arterioles &
venules specially hands & fingers
Vary with thermoregulation
Heat stress mainly increases blood
flow through A -V anastomoses of
hands & feet
Low metabolism
Characteristics.
Subdermal capillaries & venous
plexuses are special reservoirs
Alterations in blood flow can be
observed visually
Thick muscular layer
Rich nerve supply
Mainly under SNS control
Nervous control
Noradrenergic nerves, circulating epinephrine &
nor epinephrine VC
VD is due to
Reduction in VC activity
Local bradykinin in sweat glands
Local VD metabolites
VC activity is modified by
Hypothalamic response to temperature
variation
Stimulation by temperature receptors through
lateral spinothalamic tract
Triple response
Skin is stroked with blunt object
White reaction Constriction of precapillary sphincter
Skin stroked more firmly with pointed object
Red reaction redness at the site appears in
about 10 second due to capillary dilation.
Wheal local edema due to increased
permeability of capillaries.
Flare redness spread out from injury due to arteriolar dilation
Wheal
Increased capillary permeability by histamine / sub.P
Increased capillary pressure due to dilatation of precapillary
sphincter
Flare
Dilatation of arteriole, precapillary sphincters by axon reflex
Increased local blood flow increases local temperature
Abolished by local anesthesia
Axon
reflex
Flare is
due to
antidromic
conduction
in
sensory
nerve
branches
Study material
Guyton Chapter 73
Ganong 21st edition chap. 32
Thanks