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BAGIAN NINDY

PENGATURAN SEKRESI
DI PITUITARY

PENGATURAN SEKRESI
DI PITUITARY

Awal Fase Folikuler


Reserve
FSH & LH

(+
)

Estrogen

(+)

(+)

(-)

Serum
Gonadotro
pin

(+)

Activation

Secretion
FSH & LH

GnRH
(+)
Prod.
Gonado
t.

Ovary
OVARY

Pertengahan Siklus (Pre


Ovulasi)
Reserve
FSH & LH

Estrogen

activation

High Level

(+)

(+)
(+)

Secretion
FSH & LH
LH
surge

FSH
surge

Progesterone
(low level)

(+)

OVARY

GnRH
(+
)

Serum
Gonadotropi
n

Pr
Go od
na .
t. do

SI
E
KR
E
N S RY
A
UR UITA
T
(+)
GA I PIT
N
D
PE

FSH & LH

(+)

Estrogen

activation

(+)

(-)

GnRH
(+)

Secretion
FSH & LH
LH surge

FSH
surge

Progesterone
(high level)

OVARY
Ovary

d.
o
Pr ado
n
Go .

Fase Luteal (Pasca


Ovulasi)
Reserve

I
ES
R
EK
S
AN ARY
R
TU ITUIT
A
NG DI P
E
P

Serum
Gonadotr
opin

(-)

Estrogen
Progesterone
(high level)

LH (theca cells)
sintesis Androgen
FSH
proliferasi sel gran.
aromatisasi A-E2
FSH&LHR/FSH di
sel granulosa
stimulasi produksi
inhibin dan activin

LH
OMI (+)
Sintesis Prostaglandin
Elevated P :-plasminogen
- plasmin
- FSH-Surge
FSH Surge : -proteolytic enzym
activity
- FSH + E2 R/LH

P
FSH & LH
LH Maintain
Corpus
luteum
- Vascul
Steroidogenes

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