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CrackingTheDNACode

LuzGonzalez
1. He isolated the first crude extract of DNA. After his discovery, other scientists found better
ways to purify the nuclein without the nutrients and that purified substance became
known as deoxyribonucleic acid (DNA).
2. He used the microscope to see the blood cells.
3. Proteins
4. Four different nucleotides, ribose sugar, and phosphate.
5. When DNA was isolated from a strain of bacteria, it was able to transform another strain
and confer characteristics onto that second strain. DNA was carrying hereditary
information.
Erwin Chargaff

His paper on the ratios helped solve the structure of DNA. It said that the ratio
of adenine to thymine is equal, as is the ratio of cytosine to guanine.
Rosalind Franklin

An x-ray pattern of DNA triggered the idea that DNA was a helix.
Linus Pauling

His chemistry was wrong, but it helped James Watson and Francis Crick to
solve the structure of DNA.
James Watson and Francis Crick

James Watson used cardboard cutouts representing the


shapes of the DNA bases to figure out how bases pair. He realized that the adenine-thymine and
cytosine-guanine pairings fit all the dimensions.
Maurice Wilkins
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Maurice Wilkins obtained some of the first X-ray diffraction patterns of DNA
from which dimensions could be calculated.

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