CERTIFICATE OF ANALYSIS

Ritonavir impurity L

Catlog code No
S

Product Name

N
O
NH

N
O

NH

Chemical Name

O
H
N

Mol. Formula
Mol. Weight

Batch No R1312YO

Analysis Date

Quantity 25mg

Retest Date

Storage

Preserve in Air tight container, protect from direct sunlig

S.N.

Test

Result

Appearance

White solid

Solubility

Freely Soluble in Me

Identification by 1H NMR

Complies

Identification by Mass

Complies

Purity by HPLC

99.79%

Remarks: Based on 1H NMR, Mass and HPLC data, material confirm

Prepared By

Sign.
Date:
FRM/007-00

1181312
Ritonavir impurity L
(4S,5S)-4-benzyl-5-[(2S)-2-[[(2S)-3-methyl-2-[[methyl
[[2-(1-methylethyl)thiazol-4-yl]methyl]carbamoyl]amino]
butanoyl]amino]-3-phenylpropyl]oxazolidin-2-one
C33H43N5O4S
605.79 g/mol
4-Jun-15
Jun-17
sunlight and for longer storage store at 2-8 C.

in Methanol

confirms to the above product.

Approved by

Quality Control Department

CERTIFICATE OF ANALYSIS
Ritonavir impurity L

Product Name
Chemical Name
Mol. Formula
Mol. Weight
Batch No VSLS/RIT/IMP-L/15-16

Analysis Date

Quantity 25MG

Retest Date

Storage

Preserve in Air tight container, protect from direct sunlig

S.N.

Test

Result

Appearance

Off White solid

Solubility

Freely Soluble in Me

Identification by 1H NMR

Complies

Identification by Mass

Complies

Purity by HPLC

98.89%

Remarks: Based on 1H NMR, Mass and HPLC data, material confirm

Prepared By

Sign.
Date:
FRM/007-00

Ritonavir impurity L
(2S)-3-Methyl-2-[[[methyl[[2-(1-methylethyl)-4thiazolyl]methyl]amiS)-2-oxo-4-(phenylmethyl)-5oxazolidinyl]methyl]-2-phenylethyl]-butanamide
C33H43N5O4S
605.79 g/mol
24-Nov-15
Nov-16
sunlight and for longer storage store at 2-8 C.

in Methanol

confirms to the above product.

Approved by

Quality Control Department