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Gingival Crevicular Fluid

drg.Juwita Raditya Ningsih


FKG UMS
2014

Anatomy Gingival Sulcus

GCF COMPOSITION

ENZYMATIC COMPONENTS

HOST
HOST DERIVED
DERIVED
AND
ANDOTHER
OTHER
PRODUCTS
PRODUCTS

NON ENZYMATIC COMPONENTS

BACTERIA DERIVED
CELLULAR
COMPONENT

ELECTROLYTES

ORGANIC
COMPONENTS

Host derived enzymes


Acid

phosphates
Alkaline phosphatase
Alpha 1 antitrypsin
Arylsulphatse
Aspartate aminotransfarase
Chondroition sulphate
Citric acid
Cystatins
B-glucuronidase
Cathepsin
Matrix metalloproteins
Elastase
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Bacteria derived enzymes

Acid phosphatase
Alkaline phosphatase
Collagenase
Hyaluronidase
Phospholipse-A
Phospholipase-C

Cellular elements
Bacteria
Desquamated epithelial cells
Leucocytes ( PMNS, monocytes/macrophages)
Electrolytes
Potassium
Calcium
Sodium
Organic compounds
Carbohydrates-GLUCOSEHEXOSAMINE
-HEXURONIC ACID
Proteins

Metabolic end products

Lactic acid
Urea
Hydroxyproline
Endotoxins
Cytotoxic substances
Hydrogen sulphide

Cellular Elements:
The cellular elements found in the gingival
fluid include:

bacteria,
desquamated epithelial cells,
leukocytes (PMNs, lymphocytes and monocytes) which
migrate through the sulcular epithelium.

Electrolytes
Kandungan elektrolit GCF antara lain:

Potassium
Sodium
Calcium
Magnesium
Fluoride

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