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Drug Study Diclofenac
Drug Study Diclofenac
DRUG STUDY
NAME OF
DRUG
Diclofenac
CLASSIFICATION
DOSE,
FREQUENCY
AND ROUTE
Antiinflammatory
NSAID
500
/tab
,PO
MECHANISM OF
ACTION
mg Unclear.
TID Thought
to
block activity
of
cycooxygenas
e , thereby
inhibiting
inflammation
responses of
vasodilation
and swelling
and blocking
transmitions
of
painful
stimuli
INDICATIONS
CONTRAINDICATIONS
NURSING
RESPONSIBILITIES
Analgesia,
Dysmenorrhe
a, rheumatoid
arthritis,
osteoarthritis
ankylosing
spondylitis
Hypersensitivit
y to drug or
its
components,
other NSAIDs,
or aspirin
Active
GI
bleeding
or
ulcer disease
CNS:
headache,
dizziness,
drowsiness
CV: hypertension
GI:
diarrhea,
abdominal
pain,
dydpepsia, heart
burn, peptic ulcer,
GI bleeding
GU:
dysuria,
frequent
urinations,
nephritis
Hepatic:
hepatotoxicity
Skin: rash, contact
dermatitis
1.Assess
for
hypertension
2. monitor hepatic and
renal function
3. Observe for and report
signs and symptoms of
bleeding
Patient teaching
1. instruct patient to
take a drug on empty
stomach for 1 hour
before or after a meal
2. advice patient not to
lie down for 15 to 30
minutes
after
taking
drug,
to
minimize
esophageal irritation
3. instruct patient to
immediately report signs
Page | 17
or
symptoms
hypersensitivity
reaction .
DRUG STUDY
NAME OF
DRUG
CLASSIFICATIO
N
DOSE,
FREQUENCY
AND ROUTE
MECHANISM OF
ACTION
INDICATIONS
CONTRAINDICATIONS
NURSING
RESPONSIBILITIES
Page | 18
of
Ampicillin
Antibiotic
Penicillin
May
be
given
IV,
IM or PO.
Use
parentarel
routes
severe
infections,
and switch
to
oral
route
as
soon
as
possible.
Bactericidal
action against
sensitive
organism;
inhibits
synthesis
of
bacterial cell
wall, causing
cell death.
Treatment of
infections
caused
by
susceptible
strains
of
Shigella,
salmonella, E.
coli,
H.
influenza,
P.
mirabilis,
N.
gonorrhea,
enterococci,
gram-positive
organisms( pe
nicillin
Gsensitive
staphylococci,
sterptococci,
pneumococci)
Meningitis
cause
by
Neisseria
meningitidis
Unlabeled
use:
Prophylaxis in
cesarean
section
in
certain
high
Contraindicate
d with allergies
to
penicillin
cephalosporins
,
or
other
allergens.
Use cautiously
woth
renal
diorders.
CNS:
Lethargy,
hallucinations,
seizure
CV: CHF
GI:
glossitis,
stomatitis,
gastritis,
sore
mouth,
furry
tongue,
black
hairy
tongue,
nausea, vomiting,
diarrhea,
abdominal
pain,
bloody
diarrhea,
enterocolitis,
pseudomembrano
us
colitis,
nonspecific
hepatitis
GU: Nephritis
Hematologic:
Anemia,
thrombocytopenia,
leukopenia,
neutropenia,
prolonged
bleeding time
Hypersensitivity:
Rash,
fever,
Page | 19
risk patients.
wheezing,
anaphylaxis
Local:
Pain,
phlebitis,
thrombosis
at
injection
site( parenteral)
Other:
superinfectionsoral and rectal
moniliasis,
vaginitis
Page | 20