www.ranodhospital.go.

th



(Medications in the Breast-feeding mother)

1.

2.

3. toxicity

4.

5. , half-life ,

6.

7.

8.

2-3

10

1. ANAESTHETICS , Local anaesthetics , Preoperative medication

:

cup feeding
Drugs

lidocaine
ephedrine

and disturbed sleep)

atropine

(irritability

(drying of secretion

,temperature elevation and CNS disturbance)

chloralhydrate

drowsiness

diazepam

Short-acting
benzodiazepam

2.Analgesics,antipyretics, nonsteroidal anti-inflammatory drugs, drugs

used to treat gout and disease-modifying agents used in rheumatic
disorders.
Drugs

aspirin

(haemolysis,prolonged bleeding time and
metabolic acidosis)

ibuprofen

paracetamol

diclofenac

naproxen

tramadol

()

Morphine

T1/2

Pethidine

(apnea and bradycardia, cyanosis)

(apnea and bradycardia, cyanosis)
Morphine

allopurinol

colchicines

3.Antiallergics and drugs used in anaphylaxis.

Drugs

chlorphenamine

dexamethasone

epinephrine
(adrenaline)
prednisolone

4. Anticonvulsants/Antiepileptics
Drugs
carbamazepine

(jaundice,drowsiness,poor
suckling,vomiting and poor weight gain)

diazepam ,
lorazepam

(
)

magnesium sulfate

phenobarb

phenytoin

(drowsiness,poor suckling and poor

weight gain)

(cyanosis and mehaemoglobinemia)

valproic acid

(jaundice)
clonazepam(B)

5.Anti-infective Anthelminthics Antibacterials Antituberculosis

Antifungal Antiviral Antiprotozoal drugs
Drugs

albendazole

mebendazole

amoxicillin

ampicillin

benzathine penicillin

cloxacillin
dicloxacillin
amoxicillin+clavulani
c acid

clavulanic

ADR

GI

irritate

ceftazidime

ceftriaxone
cefotaxime
chloramphenicol

doxycyclin

( staining

infants teeth)

<1week
erythromycin ,
roxitromycin

gentamicin

thrush

(erythromycin

GI irritate)
and diarrhea

metronidazole

2 - 12 .

nalidixic acid (

quinolone)

1
(haemolysis,jaundice)

G-6-PD

deficiency.

norfloxacin

ofloxacin

ciprofloxacin

nitrofurantoin

1
(haemolysis,jaundice)
G-6-PD deficiency.

co-trimoxazole

1
(haemolysis,jaundice)
G-6-PD deficiency.

clindamycin
dapsone

1
(haemolysis,jaundice)
G-6-PD deficiency.
isoniazid

toxicity

rifampicin

jaundice

jaundice

toxicity

pyrazinamide

jaundice

toxicity

ethambutal

toxicity

jaundice

streptomycin

thrush

diarrhoea

amphotericin B

fluconazole

ADR
griseofuvin

aciclovir

chloroquine
primaquin
quinine

hemolysis

jaundice

1
G-6-PD deficiency.
6.Antimigraine drugs
Drugs

ergotamine

(ergotism)

propranolol

(bradycardia, hypoglycemia, and

cyanosis)
flunarizine

7.Antiparkinson drugs
Drugs
levodopa+carbidopa

levodopa

8. Drugs affecting coagulation

Drugs

heparin sodium

enoxaparin

Phytomenadione

( vitamin

K)
warfarin

9.Cardiovascular drugs
Drugs
atenolol

1
(bradycardia hypotension and cyanosis)

isosobide dinitrate

verapamil

digoxin

atenolol

(bradycardia hypotension and

cyanosis)

captopril , enalapril

hydralazine

hydrochlorothiazide (HCTZ)

methyldopa

nifedipine ,amlodipine

digoxin

dopamine

aspirin

(haemolysis , prolonged
bleeding time and metabolic acidosis)
10. Diuretics short-acting thiazide ,
loop diuretics long-acting thiazide

amiloride

furosemide

Hydrochlorothiazide (HCTZ)

spironolactone

mannitol

11 Tropical Dermtological drugs () !

Drugs

Antifungal drugs
benzoic acid+salicylic acid

clotrimazole

sodium thiosulfate

Anti-infective drugs
gentian violet

potassium permanganate

silver sulfadiazine

Anti-inflammatory and
antipruritic drugs
betamethasone

calamine lotion

coal tar

podophyllum resin

salicylic acid

Scabicides and pediculicides

benzyl benzoate

12.Gastrointestinal drugs Antacids and other antiulcer drugs

Antiemetic drugs Antispasmodic drugs
Laxatives Drugs use in
diarrhoear
Drugs

alum milk

ranitidine

omeprazole

domperidone

dimenhydrinate

irritability

metoclopamide

buscopan

simethicone

senna

magnesium hydroxide

lactulose

bisacodyl

oral rehydration salts

13. Steroid Hormones,and contraceptives

Drugs
dexamethasone

prednisolone

4 .

ethinylestradiol+levonorges
trel

ethinylestradiol
+norethisterone

levonorgestrel

medroxyprogesterone
acetate

ethinylestradiol

norethisterone

medroxyprogesterone
acetate

Thyroid and antithyroid

drugs
levothyroxine ( Lthyroxine)
propylthiouracil (PTU)

( thyroid function )

methimazole

PTU

T
10-15 mg /
14. Insulins and other antidiabetic agents
Drugs
glibenclamide

!
hypoglycemia

insulin injection

intermediate-acting insulin

metformin

(%RID < 0.3)

15. Immunologicals
Drugs

Antitetanus
immunoglobulin
Antivenum sera

Diphtheria antitoxin

Immunoglobulin (human)

Rabies immunoglobulin

BCG vaccine

diphtheria vaccine

hepatitis B vaccine

Measles vaccine

pertussis vaccine

Poliomyelitis vaccine

Tetanus vaccine

influenza vaccine

meningococcal meningitis

Mumps vaccine

Rabies vaccine(inactivated)

Rubella vaccine

16. Psychotherapeutic drugs , Drugs use in mood disorders

Drugs

chlorpromazine
drawsiness
fluphenazine
drawsiness
Typhoid vaccine

haloperidol

drawsiness

fluoxetin

colic
irritability

amitriptyline

150mg/day

carbamazepine

(jaundice,drowsiness, poor suckling ,vomiting and
poor weight gain)

fluoxetin

SE
colic irritability (
)

lithium carbonate

valproic acid

(jaundice)

diazepam

drowsiness

lorazepam

16. Drugs acting on the respiratory tract.

Drugs

Antiasthmatic drugs
beclometasone

ipratropium bromide

salbutamol

theophyllin

Antitussive
dextromethorphan

M.tussis

( alcohol )

Ammonium carbonate

bromhexine

Acetylcysteine (fluimucil)

( alcohol )

17.

Allergic
rhinitis

Beclomethason
e
(Beconase)
Fluticasone(Flo
nase)
Cromolyn(Nasa
lcrom)

Cetrizine(Z
rtec)
Loratadine
(Claritin)
Sedating
antihistami
nes
decongest
ants
Nifedipine
Verapamil
Hydralazin
e
Captopril
Enalapril

Cardiovasco
lar

Hydrochlorothi
azine
Metoprolol
tartrate
Propanolol(Ind
eral)

Depression

Sertraline
Paroxetine

Diabetes

Insulin
Glyburide
Glipizide
Tolbutamide
Phenyltoin
Carbamazepin
e

Epilepsy

Pain

Asthma

Contracepti
on

Ibuprofen
Morphine
Acetaminophe
n
Cromolyn
Nedocromil
Barrier
methode

Nortryptali
ne
Desiprami
ne
Acarbose

Atenolol
Nalolol
Sotalol
Diltiazem

Fluoxetine

Metformin
Thiazolinediones

Ethosuximi Phenobarbital
de
Valproic
sodium
Naproxen
Meperidine
Fluticason
e
Beclometh
asone
Progestin- Combined pills
only
agent(DMP
A)

 :
- :
paracetamol
(Tylenol) (NSAIDs)
Ibuprofen (Brufen)
- : Penicillin's
Cephalosporin's

- :
clotrimazole (Canesten)
Fluconazole (Difulcan)
- :

Cetirizine (Zyrtec) Loratadine (Clarityne)
pseudoephedrine

(Maxiphed)
Oxymetazoline (Iliadin)
diphenhydramine (Benadryl)
- : Aluminium Hydroxide and Magnesium

Hydroxide (Alum milk)

Sucralfate (Ulsanic), Ranitidine (Zantac)
- : Domperidone (Motilium-M)
B-6

- :
Metamucil (Mucillin) Lactulose
(Hepalac)
- : Doxepin,
Amiodarone, Lithium, Methotrexate, Tetracycline (),

Ergot, Iodides,


1. Compatible with breastfeeding

2. Compatible with breastfeeding. Monitor infant for side-effects

side-effects

3. Avoid if possible. Monitor infant for side-effects

4. Avoid if possible. May inhibit lactation

5. Avoid


radioactive

1. Breastfeeding and maternal medication. Department of Child and

Adolescent Health and Development,World Health
Organization,2003.
2. Jeanne PS,Luis SG III,Donna JB. Medications in the Breast-Feeding
Mother.
American Family Physician, July 1,2001:1-11.