Viruses:

Naked virusshell and nucleic acid. Enveloped Virus

Classification of Viruses:

Genome:
o
DNA
o
RNA

Structural symmetry:

Envelope:
o
Presence
o
Absence
Virions==complete, mature, infective viral particle.

Protection and delivery of the viral genome from a

susceptible and permissive cell to another susceptible and
permissive cell
Host Specificity:

Cell Susceptibility: cell possesses appropriate surface

receptors to allow viral attachment (not all cells can be
infected)

Cell Permissiveness: cell contains all the appropriate

components required for viral replication, including surface
receptors (leads to productive infection)
RevTxase
+ssRNA/iDNA
DNA virus families:
Retro

dsDNA (Linear, circular):

o
Polyomaviridae,
o
Adenoviridae,
o
Herpesviridae,
o
Poxviridae,
o
Papillomaviridae

Partially dsDNA (Circular):

o
Hepadnaviridae
ssRNA

(+/-) ssDNA (Linear, circular):

Orthomyxo
o
Circoviridae,
Paramyxo
o
Parvoviridae
Rhabdo
RNA virus families:
Filo
Naked

dsRNA:
Arena
o Enveloped
Reoviridae
Borna

(+) ssRNA:
o
Coronaviridae
o
Flaviviridae
o
Picornaviridae
o
Togaviridae,
o
Caliciviridae
o
Astroviridae
o
Arteriviridae
o
Hepeviridae

(+) ssRNA (diploid) with iDNA (intermediate DNA):

o
Retroviridae
(-) ssRNA (antisense, ambisense):
o
Orthomyxoviridae
o
Paramyxoviridae
o
Rhabdoviridae
o
Filoviridae
o
Arenaviridae
o
Bornaviridae

NAKED
ENVELOPED
Genomes:
--DNA:

ssDNA or dsDNA or partially dsDNA

--RNA:

Positive-polarity, single stranded (mRNA=codons)

Negative-polarity, single stranded (tRNA=anticodons)

dsDNA

ssDNA intermediate
Helical Symmetry (helicoidal or filamentous)
*assembly of icosahedral viruses: proteins bump into each other
dsRNA
and grow
Reo

proteins facet capsomere

icosahedrone
Capsid: always made of proteinprotects and packages

Host-derived envelope: surrounds capsid.

Naked Virus=more resistant

Enveloped Virus=less resistant

dsDNA

Families of viruses can cause different diseases or the

HePoHePaPo ParAde
same
diseases
+ ssRNA
RDRPoly
Herpes
Polyoma
PiToFlArCoCa AstroHepe
Hepadna
Picorna
Papilloma
Toga
Pox
Flavi
Parvo
Arteri
Adeno
Corona
Calici
Astro
Hepe