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  • Pathophysio

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    aprilrosehibaya
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    This document describes the presentation and progression of medulloblastoma in a pediatric patient. It lists factors that can contribute to medulloblastoma development such as genetic mutations and family history. The tumor arises in the cerebellum and grows along the channels of the fourth ventricle, eventually filling and blocking the ventricle. This compression of the cerebellum and brainstem leads to increased intracranial pressure, hydrocephalus, and symptoms like ataxia, nystagmus, and vomiting.

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    pathophysio

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    This document describes the presentation and progression of medulloblastoma in a pediatric patient. It lists factors that can contribute to medulloblastoma development such as genetic mutations and family history. The tumor arises in the cerebellum and grows along the channels of the fourth ventricle, eventually filling and blocking the ventricle. This compression of the cerebellum and brainstem leads to increased intracranial pressure, hydrocephalus, and symptoms like ataxia, nystagmus, and vomiting.

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    Download as docx, pdf, or txt
    28 views2 pages

    Pathophysio

    Uploaded by

    aprilrosehibaya
    This document describes the presentation and progression of medulloblastoma in a pediatric patient. It lists factors that can contribute to medulloblastoma development such as genetic mutations and family history. The tumor arises in the cerebellum and grows along the channels of the fourth ventricle, eventually filling and blocking the ventricle. This compression of the cerebellum and brainstem leads to increased intracranial pressure, hydrocephalus, and symptoms like ataxia, nystagmus, and vomiting.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
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    of 2

    al granular layer that did not disappear after the first year of life.

    Faulty mutation of the nuclear protein P53.

    Genetic: Family hx of Gorlin syndrome,


    Blue-Rubber – Bleb syndrome,

    Non-modifiable Factors
    Turcot syndrome

    Age: 2-10 yrs old


    Sex: female
    Modifiable Factors
    unknown

    Tumor arises on the vermis of the cerebellum

    Tumor grows along the channels of 4th ventricle

    Fills and blocks the 4th ventricle Compression of cerebellum

    Legend:
    Invasion and compression of brainstem
    Obstruction of CSF flow in the 4th ventricle
    Cerebellar dysfunction Yellow – factors present in patient
    White- book- based factors
    Red – symptoms elicited by patient
    Black – course of the disease

    ataxiaHx of poor coordination in upper extremities


    Brainstem dysfunction
    Increased ICP hydrocephaly

    macrocephaly
    Signs: Signs:
    Uncoordinated eye movements Sunset eyes
    Nystagmus Lethargy
    Diplopia Morning headache
    Facial weakness Daily vomiting
    Increased respiratory rate Anorexia
    Abnormal heart rate Blurry vision

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