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    Drug Eruption (Drug-Induced Dermatitis), F 42, Left Wrist.

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    Deba P Sarma
    This document discusses features to look for in diagnosing a drug eruption or drug-induced dermatitis. Key features include interface inflammation and papillary dermal edema, interface infiltrates of lymphocytes and neutrophils with papillary edema and dyskeratotic keratinocytes, and intraepidermal dyskeratotic keratinocytes without vasculitis. Additional features that support the diagnosis include hyaline bodies at the interface and dermal pigmentary incontinence. These features may also be present in drug-induced cases of erythema multiforme. The diagnosis should be correlated with clinical findings.

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    Drug Eruption (Drug-Induced Dermatitis), F 42, Left Wrist.

    Uploaded by

    Deba P Sarma
    121 views7 pages
    This document discusses features to look for in diagnosing a drug eruption or drug-induced dermatitis. Key features include interface inflammation and papillary dermal edema, interface infiltrates of lymphocytes and neutrophils with papillary edema and dyskeratotic keratinocytes, and intraepidermal dyskeratotic keratinocytes without vasculitis. Additional features that support the diagnosis include hyaline bodies at the interface and dermal pigmentary incontinence. These features may also be present in drug-induced cases of erythema multiforme. The diagnosis should be correlated with clinical findings.

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    Drug eruption ( Drug-induced dermatitis) , dermatopathology quiz, lesson in dermatopathology

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    Drug Eruption ( Drug-Induced Dermatitis), F 42, Left Wrist.

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    This document discusses features to look for in diagnosing a drug eruption or drug-induced dermatitis. Key features include interface inflammation and papillary dermal edema, interface infiltrates of lymphocytes and neutrophils with papillary edema and dyskeratotic keratinocytes, and intraepidermal dyskeratotic keratinocytes without vasculitis. Additional features that support the diagnosis include hyaline bodies at the interface and dermal pigmentary incontinence. These features may also be present in drug-induced cases of erythema multiforme. The diagnosis should be correlated with clinical findings.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPT, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as ppt, pdf, or txt
    121 views7 pages

    Drug Eruption (Drug-Induced Dermatitis), F 42, Left Wrist.

    Uploaded by

    Deba P Sarma
    This document discusses features to look for in diagnosing a drug eruption or drug-induced dermatitis. Key features include interface inflammation and papillary dermal edema, interface infiltrates of lymphocytes and neutrophils with papillary edema and dyskeratotic keratinocytes, and intraepidermal dyskeratotic keratinocytes without vasculitis. Additional features that support the diagnosis include hyaline bodies at the interface and dermal pigmentary incontinence. These features may also be present in drug-induced cases of erythema multiforme. The diagnosis should be correlated with clinical findings.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPT, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as ppt, pdf, or txt
    of 7

    Drug eruption

    ( Drug-induced dermatitis)

    Deba P Sarma, Md
    Omaha
    F 42, left wrist

    Interface inflammation, papillary dermal edema


    Interface acute and lymphocytic and neutrophilic infiltrates, papillary edema,
    dyskeratoic keratinocytes, lymphocytic and neutrophilic exocytosis
    Dyskeratotic and individual necrotic keratinocytes, interface dermatitis,
    papillary edema, no vasculitis
    Intraepidermal dyskeratotic keratinocytes, interface dermatitis
    Numerous hyaline bodies at the interface, dermal pigmentary incontinence
    Comment
     Features to look for in drug eruption:

     Interface inflammation, papillary dermal edema.

     Interface acute and lymphocytic and neutrophilic infiltrates,


    papillary edema, dyskeratoic keratinocytes, lymphocytic
    and neutrophilic exocytosis.

     Intraepidermal dyskeratotic and individual necrotic


    keratinocytes, no vasculitis.

     Hyaline bodies at the interface, dermal pigmentary


    incontinence.
     Such features may also be seen in Erythema multiforme,
    which in many cases are drug-induced. Correlate with
    clinical findings.

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