Angina pectoris

Alternative names

Angina - stable; Angina - chronic; Angina pectoris

Definition

Angina is chest pain caused by too little blood flow to the heart muscle. The pain usually begins
slowly and gets worse over a period of minutes before going away. Stable angina typically occurs
when you exert yourself, and is quickly relieved with medication or rest. It is also called chronic
angina.

Angina chest pain that lasts longer than a few minutes or occurs with rest is considered unstable
angina.

Causes, incidence, and risk factors

There are approximately 400,000 new cases of stable angina diagnosed each year, according to
the American Heart Association.

The most common cause of angina is coronary artery disease (CAD). Angina pectoris is the
medical term for this type of chest pain.

Situations that increase blood flow to the heart may cause angina in people with CAD. These
include exercise, heavy meals, and stress.

The risk factors for angina pectoris include:

• Male gender
• Cigarette smoking
• High cholesterol levels (in particular, high LDL and low HDL cholesterol)
• High blood pressure
• Diabetes
• Family history of coronary heart disease before age 55
• Sedentary lifestyle
• Obesity

Less common causes of angina include:

• Coronary artery spasm (also called Prinzmetal's angina)

• Diseases of the heart valves
• Heart failure
• Abnormal heart rhythms
• Anemia
Symptoms

Stable angina:

• Occurs after activity, stress, or exertion

• Lasts 1 to 15 minutes
• Is usually relieved with rest or nitroglycerin

The most common symptom is a feeling of tightness, heavy pressure, or squeezing or crushing
chest pain that:

• Occurs under the breastbone or slightly to the left

• Is not clearly focused in one spot
• May spread to shoulder, arm, jaw, neck, back, or other areas
• May feel like gas or indigestion

You should seek medical attention if you have new, unexplained chest pain or pressure. If you
have had angina before, call your doctor.

Immediately go to the hospital if chest pain or heaviness lasts longer than 15 minutes or is not
relieved with medication prescribed by your doctor. The pain may represent unstable angina or a
heart attack.

Signs and tests

The following tests may be done to diagnose or rule out angina:

• Blood pressure measurement

• Exercise tolerance test (stress test or treadmill test) -- may show ECG changes
• Stress echocardiogram -- may reveal problems with the heart's ability to pump blood
• Coronary angiography

Treatment

The goals of treatment are to reduce symptoms and prevent complications. If you experience
angina pain, you should:

• Rest
• Take nitroglycerin (only if prescribed by your doctor)

There are three primary forms of medication for stable angina.

1. Medications that improve long-term health include aspirin, clopidogrel (Plavix), and
cholesterol-lowering drugs.
2. Medications that improve symptoms include nitrates and calcium channel blowers.
3. Medications that do both include beta blockers and angiotensin-converting enzyme
(ACE) inhibitors.
In 2006, the U.S. Food and Drug Administration approved new type of medication
called ranolazine (Ranexa) for the treatment of chronic angina. The drug is for patients who do
not respond to traditional angina treatment. It should be used in combination with other medicals.
Your doctor will tell you which ones.

Your doctor may recommend a cardiac rehabilitation program to help improve your heart's fitness.

Some patients may need surgery such as:

• Percutanueous Transluminal Coronary Angioplasty (PTCA)

• Coronary artery bypass grafting (CABG)

Expectations (prognosis)

Stable angina usually improves with medication.

Complications

• Unstable angina
• Heart attack
• Sudden death caused by lethal arrhythmias

Calling your health care provider

Call your health care provider if any of the following occur:

• Chest pain develops that has not been evaluated

• Your angina changes in frequency, severity, duration, or character (for example, it
happens at rest or lasts longer than 15 minutes)
• Your angina requires increasing doses of nitroglycerin

Prevention

Your doctor may tell you to take nitroglycerin a few minutes in advance if you plan to perform
an activity that may trigger angina pain.

The best prevention for angina is to lower your risk for coronary heart disease.

• Stop smoking
• Lose weight if you are overweight
• Control blood pressure, diabetes, and cholesterol

Reducing risk factors may prevent the blockages from getting worse and can reduce their
severity, which reduces angina pain.

— MAHMUD CD9