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  • Pa Tho Physiology Theoretical

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    michael_1ray9
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    This document outlines the pathophysiology and modifiable risk factors of hypertension. It describes how excess sodium intake, obesity, stress, fewer nephrons, and endothelial dysfunction can lead to renal sodium retention and increased fluid volume, activating the sympathetic nervous system and renin-angiotensin system to cause venous constriction, increased cardiac output and peripheral resistance, and ultimately increased blood pressure and hypertension. Family history, age, smoking, and physical inactivity are also identified as modifiable risk factors.

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    This document outlines the pathophysiology and modifiable risk factors of hypertension. It describes how excess sodium intake, obesity, stress, fewer nephrons, and endothelial dysfunction can lead to renal sodium retention and increased fluid volume, activating the sympathetic nervous system and renin-angiotensin system to cause venous constriction, increased cardiac output and peripheral resistance, and ultimately increased blood pressure and hypertension. Family history, age, smoking, and physical inactivity are also identified as modifiable risk factors.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
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    Download as doc, pdf, or txt
    14 views1 page

    Pa Tho Physiology Theoretical

    Uploaded by

    michael_1ray9
    This document outlines the pathophysiology and modifiable risk factors of hypertension. It describes how excess sodium intake, obesity, stress, fewer nephrons, and endothelial dysfunction can lead to renal sodium retention and increased fluid volume, activating the sympathetic nervous system and renin-angiotensin system to cause venous constriction, increased cardiac output and peripheral resistance, and ultimately increased blood pressure and hypertension. Family history, age, smoking, and physical inactivity are also identified as modifiable risk factors.

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    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
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    of 1

    VII.

    Pathophysiology Modifiable risk factors:


    (Theoretical Based) -High salt intake
    -Obesity (BMI of >30kg/m2) Modifiable risk factors:
    -Stress -Family History (Genetic alteration)
    -Fewer nephrons -Age (older than 55 years for men
    - Endothelial factors and 65 years for women)
    - Diabetes Mellitus
    - Smoking
    - Physical inactivity

    Excess sodium Fewer nephrons Stress Genetic alteration Obesity Endothelial factors
    intake

    Cell
    Sympathetic membrane Hyperinsulinemia
    Renal sodium Decreased nervous system
    retention filtration surface Renin alteration
    over activity angiotensin
    excess
    Increase Fluid Venous
    volume constriction

    Increase
    contractility
    Increase
    Preload Structural
    hypertrophy

    Functional
    Increased Cardiac constriction
    Output

    Increased peripheral
    resistance
    BLOOD PRESSURE INCREASES
    resulting to HYPERTENSION

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