Jhelai

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PATHOPHYSIOLOGY

Middle age (female > male before age 50),


obesity, infection, pregnancy, hormonal
contraceptive, celiac disease. Cirrhosis,
pancreatitis, diabetes mellitus

Cholelithiasis
Refers to the formation of calculi
(e.g. gallstones in the gallbladder)

Major constituents are cholesterol and


pigment

Cholecystectomy Gallstone in bile Pain Fever Nausea and Jaundice


duct vomiting

Removal of the There is inflammation Increase


gallbladder after Bile stasis due to infection Gastric irritation bilirubin
ligation of the
cystic duct

Bile accumulates Bacterial Abnormal fat


Body will return to in the liver proliferation digestion There is restlessness
normal function and Increase in RR,
temp, PR and WBC
values
Gallbladder and Diarrhea
Recovery Cholestatic duct infection

Biliary
cirrhosis Rupture of Cholecystitis If not treated
gallbladder if

Peritonitis Death

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