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    Systemic Lupus Erythematosus (SLE) : Presented by Manny Ramos RN, MSN

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    jhun27
    Systemic Lupus Erythematosus (SLE) is a chronic inflammatory autoimmune disease that can damage any part of the body. It is more common in women of childbearing age, especially those of African American, Hispanic, or Asian descent. Symptoms can include joint pain, skin rashes, fatigue, kidney problems, and neurological issues. Diagnosis involves blood tests to detect autoantibodies and complement levels. Treatment depends on severity but may include medications like corticosteroids, antimalarials, immunosuppressants, and dialysis for kidney failure. Nursing care focuses on protecting skin from sun damage, monitoring for infections, supporting health maintenance, and ensuring compliance with complex treatment plans.

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    Systemic Lupus Erythematosus (SLE) : Presented by Manny Ramos RN, MSN

    Uploaded by

    jhun27
    32 views8 pages
    Systemic Lupus Erythematosus (SLE) is a chronic inflammatory autoimmune disease that can damage any part of the body. It is more common in women of childbearing age, especially those of African American, Hispanic, or Asian descent. Symptoms can include joint pain, skin rashes, fatigue, kidney problems, and neurological issues. Diagnosis involves blood tests to detect autoantibodies and complement levels. Treatment depends on severity but may include medications like corticosteroids, antimalarials, immunosuppressants, and dialysis for kidney failure. Nursing care focuses on protecting skin from sun damage, monitoring for infections, supporting health maintenance, and ensuring compliance with complex treatment plans.

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    Systemic Lupus Erythematosus (SLE) is a chronic inflammatory autoimmune disease that can damage any part of the body. It is more common in women of childbearing age, especially those of African American, Hispanic, or Asian descent. Symptoms can include joint pain, skin rashes, fatigue, kidney problems, and neurological issues. Diagnosis involves blood tests to detect autoantibodies and complement levels. Treatment depends on severity but may include medications like corticosteroids, antimalarials, immunosuppressants, and dialysis for kidney failure. Nursing care focuses on protecting skin from sun damage, monitoring for infections, supporting health maintenance, and ensuring compliance with complex treatment plans.

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    32 views8 pages

    Systemic Lupus Erythematosus (SLE) : Presented by Manny Ramos RN, MSN

    Uploaded by

    jhun27
    Systemic Lupus Erythematosus (SLE) is a chronic inflammatory autoimmune disease that can damage any part of the body. It is more common in women of childbearing age, especially those of African American, Hispanic, or Asian descent. Symptoms can include joint pain, skin rashes, fatigue, kidney problems, and neurological issues. Diagnosis involves blood tests to detect autoantibodies and complement levels. Treatment depends on severity but may include medications like corticosteroids, antimalarials, immunosuppressants, and dialysis for kidney failure. Nursing care focuses on protecting skin from sun damage, monitoring for infections, supporting health maintenance, and ensuring compliance with complex treatment plans.

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    Systemic Lupus

    Erythematosus (SLE)
    Presented by
    Manny Ramos RN, MSN
    Systemic Lupus Erythematosus
    (SLE)
    • chronic inflammatory immune complex
    • connective tissue disease
    • Mostly females of childbearing age: more
    common in African Americans, Hispanics,
    Asians
    • Cause is unknown, causative factors are
    genetic, environmental, and hormonal
    • chronic case with periods of remissions
    and exacerbations
    Pathophysiology

    • Autoantibodies
    • tissue damage in multiple organs
    • Reaction to some medications
    (procainamide, hydralazine) causes a
    syndrome similar to lupus
    Assessment
    • Early manifestations: fever, anorexia,
    malaise, weight loss, multiple arthralgias
    and symmetric non-deforming polyarthritis
    • Skin: butterfly rash across the cheeks and
    bridge of the nose; maculopapular rash
    upon sun exposure; alopecia
    • Renal: 50% with proteinuria, cellular casts,
    and nephrotic syndrome; 10% develop
    renal failure
    Assessment
    • Hematologic: anemia, leukopenia,
    thrombocytopenia
    • Cardiovascular: pericarditis, vasculitis,
    Raynaud’s phenomenon, endocarditis
    • Pulmonary: pleurisy, pleural effusion
    • Neurologic: organic brain syndrome, psychosis,
    seizures
    • Ocular: conjunctivitis, photophobia, retinal
    vasculitis
    • GI : anorexia, nausea, abdominal pain, diarrhea
    Diagnostic tests

    • Anti-DNA
    • ESR elevated
    • Serum complement levels are low (used in
    development of antigen-antibody complexes)
    • CBC: severe anemia, leukopenia with
    lymphcytopenia, thrombocytopenia
    • Urinalysis: mild proteinuria, hematuria, blood cell
    casts
    • BUN and creatinine
    • Kidney biopsy
    Collaborative Care
    • Mild cases: supportive care, aspirin,
    NSAIDs
    • Antimalarial drugs for skin and arthritic
    manifestations
    • Severe cases: high-dose corticosteroid,
    immunosuppressive agents
    (cyclophosphamide or azathioprine)
    • ESRD: dialysis and kidney transplantation
    Nursing Care
    • Impaired skin integrity: sunscreen, avoid sun
    • Ineffective Protection: aseptic techniques,
    monitor for signs of infection
    • Impaired Health Maintenance: physical and
    psychological needs
    • Home Care
    a. Compliance with treatment plan
    b. Wearing medical identification
    c. Family planning
    d. Referral to home nursing care, resources and
    support groups

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